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Vanda Pharmaceuticals

🇺🇸United States
Ownership
-
Employees
203
Market Cap
$311.8M
Website
Introduction

Vanda Pharmaceuticals, Inc. engages in the development and commercialization of therapies for high unmet medical needs. The firm intends to treat schizophrenia, jet lag disorder, atopic dermatitis, central nervous system disorders, and circadian rhythm sleep disorder. Its product portfolio includes HETLIOZ, Fanapt, Tradipitant, Trichostatin, and AQW051. The company was founded by Mihael Hristos Polymeropoulos and Argeris N. Karabelas in 2002 and is headquartered in Washington, DC.

Tolerability and Pharmacokinetics of Iloperidone in Adolescent Patients

Phase 1
Completed
Conditions
Safety and Tolerability of Iloperidone
Interventions
First Posted Date
2011-12-19
Last Posted Date
2016-06-13
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
33
Registration Number
NCT01495169
Locations
🇺🇸

Novartis Investigative Site, Salt Lake City, Utah, United States

Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2011-11-22
Last Posted Date
2014-02-17
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
60
Registration Number
NCT01477619
Locations
🇺🇸

Bio-Kinetic Clinical Applications, Springfield, Missouri, United States

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

Phase 3
Completed
Conditions
Non-24-Hour Sleep-Wake Disorder
Interventions
Drug: Placebo
First Posted Date
2011-09-08
Last Posted Date
2014-10-10
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
20
Registration Number
NCT01430754
Locations
🇺🇸

PAB Clinical Research Inc., Brandon, Florida, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

🇺🇸

Todd J. Swick, M.D., P.A., Houston, Texas, United States

and more 19 locations

Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder

Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: placebo
First Posted Date
2011-09-05
Last Posted Date
2015-06-19
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
507
Registration Number
NCT01428661
Locations
🇺🇸

Vanda Investigational Site, Brown Deer, Wisconsin, United States

Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception

Phase 3
Completed
Conditions
Non-24-Hour Sleep-Wake Disorder
Interventions
First Posted Date
2011-09-05
Last Posted Date
2015-04-21
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
200
Registration Number
NCT01429116
Locations
🇺🇸

SleepMed, Inc. - Columbia, Columbia, South Carolina, United States

🇺🇸

SDS Clinical Trials Inc., Orange, California, United States

🇺🇸

VA Palo Alto Health Care System/PAIRE (San Fransisco Bay Area), Palo Alto, California, United States

and more 19 locations

A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2011-07-26
Last Posted Date
2014-02-17
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT01402076
Locations
🇺🇸

Bio-Kinetic Clinical Applications, Springfield, Missouri, United States

Relapse Prevention Study in Patients With Schizophrenia

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2011-02-08
Last Posted Date
2023-07-17
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
635
Registration Number
NCT01291511
Locations
🇺🇦

Vanda Investigive Site, Kharkiv, Ukraine

🇺🇦

Vanda Investigative Site, Vinnytsya, Ukraine

Pharmacokinetics of Tasimelteon in Subjects With Mild or Moderate Hepatic Impairment

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2011-01-06
Last Posted Date
2014-02-17
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
29
Registration Number
NCT01271387
Locations
🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

Safety Study of Tasimelteon for Treatment of Non-24-Hour-Sleep-Wake Disorder in Blind Individuals With No Light Perception

Phase 3
Active, not recruiting
Conditions
Non 24 Hour Sleep Wake Disorder
Interventions
First Posted Date
2010-10-11
Last Posted Date
2024-04-03
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
140
Registration Number
NCT01218789

Patient Registry of Blind Subjects With Sleep-related Problems

Recruiting
Conditions
Sleep-wake Disorder in Blind Individuals
Interventions
Other: Data collection on blindness and sleep problems
First Posted Date
2010-09-06
Last Posted Date
2020-06-24
Lead Sponsor
Vanda Pharmaceuticals
Target Recruit Count
10000
Registration Number
NCT01195558
Locations
🇺🇸

Vanda Pharmaceuticals, Washington, District of Columbia, United States

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