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AELIS FARMA

🇫🇷France
Ownership
-
Employees
-
Market Cap
-
Website

Clinical Trials

9

Active:0
Completed:7

Trial Phases

2 Phases

Phase 1:7
Phase 2:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (9 trials with phase data)• Click on a phase to view related trials

Phase 1
7 (77.8%)
Phase 2
2 (22.2%)

Drug-Drug Interaction Between THC and AEF0117

Phase 1
Not yet recruiting
Conditions
Cannabis Abuse
Interventions
Drug: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one
Drug: Placebo
First Posted Date
2024-05-02
Last Posted Date
2024-11-28
Lead Sponsor
Aelis Farma
Target Recruit Count
24
Registration Number
NCT06395688

Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome

Phase 1
Completed
Conditions
Down Syndrome
Interventions
Drug: Placebo
First Posted Date
2023-02-28
Last Posted Date
2024-10-10
Lead Sponsor
Aelis Farma
Target Recruit Count
40
Registration Number
NCT05748405
Locations
🇪🇸

Hospital del Mar Medical Research Institute (IMIM),, Barcelona, Catalonia, Spain

🇪🇸

Sant Pau Memory Clinic, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

🇪🇸

Unidad de Adultos con Síndrome de Down, Hospital de La Princesa, Madrid, Spain

Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects

Phase 1
Completed
Conditions
Marijuana Abuse
Interventions
First Posted Date
2022-09-26
Last Posted Date
2023-04-07
Lead Sponsor
Aelis Farma
Target Recruit Count
8
Registration Number
NCT05554926
Locations
🇺🇸

Labcorp Clinical Research Unit Inc., Madison, Wisconsin, United States

The Effect of Food on the Oral Bioavailability of AEF0117 in Healthy Volunteers

Phase 1
Terminated
Conditions
Marijuana Abuse
Interventions
Drug: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one in fasting condition
Drug: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one in fed condition
First Posted Date
2022-07-11
Last Posted Date
2024-07-12
Lead Sponsor
Aelis Farma
Target Recruit Count
24
Registration Number
NCT05451017
Locations
🇺🇸

Substance Use Research Center, New York, New York, United States

Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD)

Phase 2
Completed
Conditions
Marijuana Abuse
Interventions
Drug: Placebo oral capsule
First Posted Date
2022-04-12
Last Posted Date
2024-07-30
Lead Sponsor
Aelis Farma
Target Recruit Count
333
Registration Number
NCT05322941
Locations
🇺🇸

Cedar clinical research, Phoenix, Arizona, United States

🇺🇸

CenExel CNR, Garden Grove, California, United States

🇺🇸

UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, California, United States

and more 8 locations
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News

Aelis Farma's AEF0117 Fails Phase 2B Trial for Cannabis Use Disorder

• Aelis Farma's AEF0117 did not meet its primary endpoint of reducing cannabis use to one day or less per week in patients with moderate to severe cannabis use disorder (CUD). • The Phase 2B trial also failed to meet secondary endpoints, including complete cessation of marijuana use or reduction to two days or less per week. • Indivior, which had an option to license AEF0117, announced it does not currently expect to exercise this option due to the lack of separation from placebo in the trial. • AEF0117 was well-tolerated, with adverse events similar across treatment groups, including placebo, indicating no significant safety concerns.

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