WAKE FOREST UNIVERSITY HEALTH SCIENCES

🇺🇸United States

Country: 🇺🇸United States

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Clinical Trials

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Phase 2

Completed

Conditions: Adult Langerhans Cell Histiocytosis
Adult Acute Lymphoblastic Leukemia in Remission
Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)
Adult Grade III Lymphomatoid Granulomatosis
Angioimmunoblastic T-cell Lymphoma
Contiguous Stage II Adult Burkitt Lymphoma
Contiguous Stage II Adult Diffuse Large Cell Lymphoma
Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma
Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma

Interventions: Drug: deferasirox
Other: laboratory biomarker analysis
Other: enzyme-linked immunosorbent assay

First Posted Date: 2011-01-10

Last Posted Date: 2018-09-07

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 16

Registration Number: NCT01273766

Locations: 🇺🇸
Comprehensive Cancer Center of Wake Forest University, Winston-Salem, North Carolina, United States

Telephone Psychotherapy for Late-Life Generalized Anxiety Disorder (GAD)

Not Applicable

Completed

Conditions: Generalized Anxiety Disorder

Interventions: Behavioral: nondirective supportive therapy
Behavioral: cognitive behavioral therapy

First Posted Date: 2010-12-14

Last Posted Date: 2018-08-29

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 141

Registration Number: NCT01259596

Locations: 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors

Phase 2

Terminated

Conditions: Hypertension
Unspecified Adult Solid Tumor, Protocol Specific

Interventions: Other: laboratory biomarker analysis
Drug: lisinopril
Drug: losartan potassium
Drug: ramipril
Drug: benazepril hydrochloride

First Posted Date: 2010-11-04

Last Posted Date: 2018-08-28

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 6

Registration Number: NCT01234922

Locations: 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

Yoga Therapy in Treating Patients With Malignant Brain Tumors

Not Applicable

Terminated

Conditions: Adult Ependymoma
Adult Gliosarcoma
Adult Grade II Meningioma
Adult Meningeal Hemangiopericytoma
Adult Anaplastic Oligodendroglioma
Adult Diffuse Astrocytoma
Adult Ependymoblastoma
Adult Giant Cell Glioblastoma
Adult Mixed Glioma
Adult Pineal Gland Astrocytoma

Interventions: Procedure: yoga therapy
Other: questionnaire administration
Procedure: quality-of-life assessment

First Posted Date: 2010-11-04

Last Posted Date: 2018-07-03

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 9

Registration Number: NCT01234805

Locations: 🇺🇸
Comprehensive Cancer Center of Wake Forest University, Winston-Salem, North Carolina, United States

Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery

Phase 1

Terminated

Conditions: Mucinous Adenocarcinoma of the Rectum
Stage IIA Rectal Cancer
Stage IIB Rectal Cancer
Stage IIC Rectal Cancer
Stage IIIB Rectal Cancer
Stage IIIC Rectal Cancer

Interventions: Drug: paricalcitol
Radiation: radiation therapy
Other: laboratory biomarker analysis
Drug: fluorouracil

First Posted Date: 2010-09-09

Last Posted Date: 2018-07-02

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 2

Registration Number: NCT01197664

Locations: 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

L-Carnitine Administration in Early Sepsis

Phase 1

Terminated

Conditions: Septic Shock

Interventions: Drug: L-Carnitine
Drug: Normal Saline

First Posted Date: 2010-09-02

Last Posted Date: 2022-04-22

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 31

Registration Number: NCT01193777

Locations: 🇺🇸
University of Mississippi Medical Center, Jackson, Mississippi, United States
🇺🇸
Carolinas Medical Center, Charlotte, North Carolina, United States

Intravenous Interferon During Liver Transplant

Not Applicable

Completed

Conditions: Hepatitis C
Cirrhosis

Interventions: Drug: IV interferon

First Posted Date: 2010-09-01

Last Posted Date: 2022-04-21

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 15

Registration Number: NCT01192698

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas

Phase 2

Completed

Conditions: Brain Tumors

Interventions: Drug: Poly ICLC

First Posted Date: 2010-08-25

Last Posted Date: 2023-06-12

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 23

Registration Number: NCT01188096

Locations: 🇺🇸
RADY Children's Hospital, San Diego, California, United States
🇺🇸
Children's Healthcare of Atlanta, Atlanta, Georgia, United States

Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer

Not Applicable

Completed

Conditions: Liver Cancer
Adrenal Cancer
Non-Small-Cell Lung Carcinoma

Interventions: Radiation: stereotactic body radiation therapy

First Posted Date: 2010-08-20

Last Posted Date: 2019-11-29

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 29

Registration Number: NCT01185639

Locations: 🇺🇸
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
🇺🇸
Coastal Carolina Radiation Oncology, Wilmington, North Carolina, United States

Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients

Not Applicable

Completed

Conditions: Tibial Fractures
Femoral Fractures

Interventions: Procedure: Wand technique
Procedure: free-hand

First Posted Date: 2010-08-17

Last Posted Date: 2023-05-16

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 55

Registration Number: NCT01183078

Locations: 🇺🇸
Wake Forest University Health Sciences - CompRehab, Winston-Salem, North Carolina, United States

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