Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase
Phase 2
Recruiting
- Conditions
- Systemic InflammationCardiopulmonary-bypass
- Interventions
- Drug: RESCAP®Drug: placebo
- First Posted Date
- 2017-02-13
- Last Posted Date
- 2024-04-19
- Lead Sponsor
- Alloksys Life Sciences B.V.
- Target Recruit Count
- 1250
- Registration Number
- NCT03050476
- Locations
- 🇧🇪
Dept. of Anesthesia and Intensive Care, AZ Maria Middelares, Gent, Belgium
🇷🇺Almazov Heart Center, St Petersburg, Russian Federation
🇩🇪Klinik für Herzchirurgie, Universitätsklinik, Leipzig, Germany
Bovine Intestinal Alkaline Phosphatase (bIAP) Modulating Rheumatoid Arthritis
Phase 1
Completed
- Conditions
- Acute Rheumatoid Arthritis
- Interventions
- Drug: s.c. injections of bovine intestinal Alkaline Phosphatase
- First Posted Date
- 2011-08-15
- Last Posted Date
- 2015-03-10
- Lead Sponsor
- Alloksys Life Sciences B.V.
- Target Recruit Count
- 6
- Registration Number
- NCT01416493
- Locations
- 🇬🇧
Maidstone Hospital, Dept. Rheumatology, Maidstone, Kent, United Kingdom
Efficacy and Safety of Bovine Intestinal Alkaline Phosphatase (bIAP) During Heart Surgery
Phase 3
Completed
- Conditions
- Inflammation
- Interventions
- Drug: bIAP bolus and 8h infusionDrug: placebo bolus and 8h infusion
- First Posted Date
- 2010-06-15
- Last Posted Date
- 2016-09-20
- Lead Sponsor
- Alloksys Life Sciences B.V.
- Target Recruit Count
- 53
- Registration Number
- NCT01144611
- Locations
- 🇳🇱
Catharina Ziekenhuis, Dept. CardioThoracic Surgery, Eindhoven, Netherlands
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