Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.
Phase 1
Not yet recruiting
- Conditions
- Tuberous Sclerosis Complex (TSC)Focal Cortical DysplasiaOther Neurological Disorders
- Interventions
- Drug: Radiprodil + co-administered drugs
- First Posted Date
- 2025-05-16
- Last Posted Date
- 2025-05-16
- Lead Sponsor
- GRIN Therapeutics, Inc.
- Target Recruit Count
- 18
- Registration Number
- NCT06975605
- Locations
- π¦πΊ
Nucleus Network Melbourne, Melbourne, Victoria, Australia
Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults
Phase 1
Recruiting
- Conditions
- Tuberous Sclerosis Complex (TSC)Focal Cortical DysplasiaOther Neurological Disorders
- Interventions
- Drug: Radiprodil with CarbamazepineDrug: Radiprodil with Itraconazole
- First Posted Date
- 2025-05-11
- Last Posted Date
- 2025-05-22
- Lead Sponsor
- GRIN Therapeutics, Inc.
- Target Recruit Count
- 36
- Registration Number
- NCT06965881
- Locations
- π¦πΊ
Q-Pharm Pty Ltd, Brisbane, Queensland, Australia
π¦πΊNucleus Network Pty Ltd, Melbourne, Victoria, Australia
Astroscape: a Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients with TSC or FCD Type II
Phase 1
Recruiting
- Conditions
- Focal Cortical DysplasiaTuberous Sclerosis Complex
- Interventions
- First Posted Date
- 2024-04-30
- Last Posted Date
- 2024-12-09
- Lead Sponsor
- GRIN Therapeutics, Inc.
- Target Recruit Count
- 30
- Registration Number
- NCT06392009
- Locations
- π¦πΊ
Queensland Children Hospital, South Brisbane, Australia
π§πͺUniversitair Ziekenhuis Antwerpen (UZA), Antwerp, Belgium
π§πͺUniversity Hospitals Leuven, Pediatric Neurology, Leuven, Belgium
Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder
- First Posted Date
- 2023-04-19
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- GRIN Therapeutics, Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT05818943
- Locations
- π³π±
UMC Utrecht - Wilhelmina Kinderziekenhuis, Polikliniek Kinderneurologie, Utrecht, Netherlands
πͺπΈUniversitat de Barcelona - Hospital Sant Joan de Deu Barcelona (HSJDB), Barcelona, Spain
πΊπΈMid-Atlantic Epilepsy and Sleep Center, Bethesda, Maryland, United States
Β© Copyright 2025. All Rights Reserved by MedPath