DeepMed Research

National Heart, Lung, and Blood Institute

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Phase 2

Recruiting

Conditions: Severe Aplastic Anemia (SAA)
Hypo-Plastic Myelodysplastic Syndrome (MDS)
Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions: Drug: Cyclophosphamide
Other: Peripheral Blood Stem Cells

First Posted Date: 2018-05-11

Last Posted Date: 2025-03-27

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 56

Registration Number: NCT03520647

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Effectiveness of the Hepatitis B Vaccine Post-Hematopoietic Stem Cell Transplant

Completed

Conditions: Hepatitis B

First Posted Date: 2018-04-30

Last Posted Date: 2022-02-07

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 52

Registration Number: NCT03511794

Locations: 🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States

Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

Completed

Conditions: Sickle Cell Disease (SCD)

First Posted Date: 2018-03-27

Last Posted Date: 2023-07-17

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 65

Registration Number: NCT03478917

Locations: 🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States

Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement

Not Applicable

Terminated

Conditions: Aortic Stenosis

Interventions: Device: Transcaval closure device (TCD)

First Posted Date: 2018-02-14

Last Posted Date: 2023-03-14

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 12

Registration Number: NCT03432494

Locations: 🇺🇸
MedStar Washington Hospital Center, Washington, District of Columbia, United States
🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸
Henry Ford Hospital, Detroit, Michigan, United States

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation

Not Applicable

Completed

Conditions: Native and Valve in Valve Aortic Valve Failure

Interventions: Device: ASHI_INTECC Astato XS 20 0.014 guidewire

First Posted Date: 2017-12-22

Last Posted Date: 2021-03-18

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 31

Registration Number: NCT03381989

Locations: 🇺🇸
Medstar Washington Hospital Center, Washington, District of Columbia, United States
🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
🇺🇸
University of Washington, Seattle, Washington, United States

and more 1 locations

Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

Phase 2

Recruiting

Conditions: Cardiovascular Disease

Interventions: Drug: control olive oil (COO)
Drug: palmitoleate-rich oil (PLO)

First Posted Date: 2017-12-14

Last Posted Date: 2025-05-20

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 110

Registration Number: NCT03372733

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Phase 1

Active, not recruiting

Conditions: Kidney Cancer

Interventions: Biological: cell infusion

First Posted Date: 2017-11-28

Last Posted Date: 2024-12-03

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 17

Registration Number: NCT03354390

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC)

Completed

Conditions: Congenital Heart Disease

First Posted Date: 2017-11-20

Last Posted Date: 2020-01-18

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 6260

Registration Number: NCT03347214

Locations: 🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

Not Applicable

Recruiting

Conditions: CAD

Interventions: Device: MRI scans - obj 3
Device: MRI scan - obj 1
Device: MRI scans - obj 4
Device: MRI scans - obj 2

First Posted Date: 2017-11-06

Last Posted Date: 2025-05-06

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 2850

Registration Number: NCT03331380

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Low-Dose Danazol for the Treatment of Telomere Related Diseases

Phase 2

Recruiting

Conditions: Telomere Disease

Interventions: Drug: Danazol

First Posted Date: 2017-10-17

Last Posted Date: 2025-04-04

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 40

Registration Number: NCT03312400

Locations: 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States

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