Clinical Trials
2.6k
Trial Phases
6 Phases
Drug Approvals
92
Clinical Trials
Distribution across different clinical trial phases (2074 trials with phase data)• Click on a phase to view related trials
A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers
- First Posted Date
- 2025-09-16
- Last Posted Date
- 2025-09-16
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 46
- Registration Number
- NCT07176975
- Locations
- 🇯🇵
National Cancer Center Hospital East, Chiba, Kashiwa, Japan
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
- Conditions
- Healthy
- Interventions
- Drug: vicadrostat / empagliflozin combination 1Drug: vicadrostat / empagliflozin 2
- First Posted Date
- 2025-08-21
- Last Posted Date
- 2025-09-19
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 32
- Registration Number
- NCT07133399
- Locations
- 🇩🇪
CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
- Conditions
- Chronic Kidney Disease
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-08-06
- Last Posted Date
- 2025-09-16
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 120
- Registration Number
- NCT07107945
- Locations
- 🇸🇬
National University Hospital, Singapore, Singapore
🇺🇸University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸Phoenix Children's Hospital, Phoenix, Arizona, United States
A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Nerandomilast in the Blood
- First Posted Date
- 2025-08-03
- Last Posted Date
- 2025-08-27
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 16
- Registration Number
- NCT07100964
- Locations
- 🇩🇪
CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany
A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the Blood
- First Posted Date
- 2025-07-24
- Last Posted Date
- 2025-09-16
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 16
- Registration Number
- NCT07081932
- Locations
- 🇩🇪
Humanpharmakologisches Zentrum Biberach, Biberach, Germany
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News
Roche Acquires 89bio for $3.5 Billion to Strengthen MASH Treatment Pipeline
Roche announced a definitive merger agreement to acquire 89bio for $14.50 per share in cash plus contingent value rights, totaling up to $3.5 billion.
UPC Court of Appeal Grants First Pharmaceutical Preliminary Injunction, Setting New Standard for Generic Drug Market Entry
The Unified Patent Court's Court of Appeal granted its first preliminary injunction in the pharmaceutical sector, blocking Zentiva from launching generic versions of Boehringer Ingelheim's Ofev across 17 European territories.
FDA Accepts First Non-Invasive Surrogate Endpoint for MASH Clinical Trials
The FDA has accepted Echosens' Letter of Intent to qualify liver stiffness measurement by FibroScan® as the first non-invasive surrogate endpoint for MASH clinical trials.
DAPA ACT HF-TIMI 68 Trial Shows Promise for In-Hospital SGLT2 Inhibitor Initiation Despite Missing Primary Endpoint
The DAPA ACT HF-TIMI 68 trial failed to show significant improvement in cardiovascular death or worsening heart failure when starting dapagliflozin during acute heart failure hospitalization, with 10.9% of treated patients versus 12.7% of placebo patients experiencing events at 60 days.
Controlled Release Drug Delivery Market Expands with Major Pharma Investment in Precision Medicine Technologies
Major pharmaceutical companies including AbbVie, AstraZeneca, and Merck are actively developing controlled drug release systems to enhance treatment of chronic diseases, cancer, and neurological disorders.
Boehringer Ingelheim Partners with AnGes for HGF Gene Therapy Manufacturing Ahead of FDA Filing
Boehringer Ingelheim has signed a contract development and manufacturing agreement with AnGes for the drug substance of their investigational hepatocyte growth factor gene therapy targeting peripheral arterial disease.
Molecular Partners Appoints Martin Steegmaier as Chief Scientific Officer to Advance DARPin Therapeutics Pipeline
Molecular Partners has appointed Martin Steegmaier, Ph.D. as Chief Scientific Officer effective October 1, 2025, bringing extensive oncology drug development experience from senior roles at Roche, MorphoSys, Boehringer Ingelberg, and SOTIO Biotech.
FDA Approves Boehringer Ingelheim's HERNEXEOS as First-in-Class HER2 TKI for Rare Lung Cancer Subset
The FDA granted accelerated approval to HERNEXEOS (zongertinib) in August 2025, marking the first oral therapy specifically targeting HER2 tyrosine kinase domain mutations in non-squamous NSCLC.
Boehringer Ingelheim Partners with Re-Vana for $1B Extended-Release Eye Therapy Development
Boehringer Ingelheim and Re-Vana Therapeutics announced a strategic collaboration to develop extended-release ophthalmic therapies using Re-Vana's drug delivery technology that releases treatments over 6-12 months.
Avalyn Pharma Raises $100M to Advance Inhaled Pulmonary Fibrosis Therapies
Avalyn Pharma secured $100 million in an oversubscribed Series D financing round to advance inhaled formulations of existing pulmonary fibrosis drugs pirfenidone and nintedanib.