Boehringer Ingelheim USA Corporation

🇺🇸United States

Country: 🇺🇸United States

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Clinical Trials

A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study

Phase 3

Terminated

Conditions: Schizophrenia

Interventions: Drug: BI 425809

First Posted Date: 2022-01-27

Last Posted Date: 2025-05-28

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 1362

Registration Number: NCT05211947

Locations: 🇺🇸
Advanced Research Center, Inc., Anaheim, California, United States
🇺🇸
Clinical Innovations, Inc, Bellflower, California, United States
🇺🇸
ProScience Research Group, Culver City, California, United States

and more 300 locations

A Study in Healthy People to Test How 2 Different Formulations of BI 695501 Are Taken up by the Body When Given as an Injection

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BI 695501 - higher concentration
Drug: BI 695501 - lower concentration

First Posted Date: 2022-01-24

Last Posted Date: 2024-03-15

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 200

Registration Number: NCT05203289

Locations: 🇺🇸
QPS MO, Springfield, Missouri, United States
🇺🇸
Miami Research Associates, Inc, Miami, Florida, United States

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

Phase 1

Recruiting

Conditions: Obesity

Interventions: Drug: BI 456906
Drug: Semaglutide

First Posted Date: 2022-01-21

Last Posted Date: 2024-11-12

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 30

Registration Number: NCT05202353

Locations: 🇳🇱
Amsterdam UMC, location VUMC, Amsterdam, Netherlands

An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options

Phase 3

Completed

Conditions: Generalized Pustular Psoriasis

Interventions: Drug: spesolimab

First Posted Date: 2022-01-20

Last Posted Date: 2025-02-25

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 11

Registration Number: NCT05200247

Locations: 🇯🇵
Tokyo Medical University Hospital, Tokyo, Shinjuku-ku, Japan
🇯🇵
Tohoku University Hospital, Miyagi, Sendai, Japan
🇯🇵
Jichi Medical University Hospital, Tochigi, Shimotsuke, Japan

and more 6 locations

A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease

Phase 2

Completed

Conditions: Kidney Disease, Chronic

Interventions: Drug: BI 690517
Drug: Placebo to BI 690517
Drug: Empagliflozin
Drug: Placebo to empagliflozin

First Posted Date: 2022-01-10

Last Posted Date: 2024-10-22

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 714

Registration Number: NCT05182840

Locations: 🇨🇦
Toronto General Hospital, Toronto, Ontario, Canada
🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸
PrimeCare Medical Group, Houston, Texas, United States

and more 199 locations

A Study in Healthy Japanese and Chinese Men to Test How Well Different Doses of BI 706321 Are Tolerated

Phase 1

Terminated

Conditions: Healthy

Interventions: Drug: BI 706321
Drug: Placebo

First Posted Date: 2022-01-10

Last Posted Date: 2024-08-20

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 48

Registration Number: NCT05183360

Locations: 🇯🇵
SOUSEIKAI Sumida Hospital, Tokyo, Sumida-ku, Japan

A Study in Healthy Japanese Men to Test How Well Different Doses of BI 1291583 Are Tolerated

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BI 1291583
Drug: Placebo

First Posted Date: 2022-01-10

Last Posted Date: 2022-08-11

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 36

Registration Number: NCT05183347

Locations: 🇯🇵
SOUSEIKAI Sumida Hospital, Tokyo, Sumida-ku, Japan

A Study in the US Based on Pharmacy and Medical Claims That Compares How Well Stiolto® and Trelegy® Work in People With Chronic Obstructive Pulmonary Disease (COPD)

Completed

Conditions: Pulmonary Disease, Chronic Obstructive

Interventions: Device: Stiolto Respimat
Device: Trelegy Ellipta
Drug: Tiotropium + Olodaterol (5/5 mcg)
Drug: Fluticasone Furoate + Umeclidinium + Vilanterol (100/62.5/25 mcg)

First Posted Date: 2021-12-27

Last Posted Date: 2023-10-19

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 9117

Registration Number: NCT05169424

Locations: 🇺🇸
eMax health, White Plains, New York, United States

To Assess the Risk of Acute Pancreatitis in Patients With Type 2 Diabetes Mellitus Treated With Empagliflozin

Completed

Conditions: Diabetes Mellitus, Type 2

Interventions: Drug: Oral non-incretin/non-sodium glucose co-transporter-2 inhibitors (SGLT2)-containing hypoglycaemic agents
Drug: empagliflozin

First Posted Date: 2021-12-17

Last Posted Date: 2024-05-02

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 494679

Registration Number: NCT05162014

Locations: 🇩🇪
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Live

Phase 2

Terminated

Conditions: Hypertension, Portal

Interventions: Drug: Avenciguat (BI 685509)
Drug: Placebo matching Avenciguat (BI 685509)

First Posted Date: 2021-12-17

Last Posted Date: 2024-12-27

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 80

Registration Number: NCT05161481

Locations: 🇯🇵
Kitasato University Hospital, Kanagawa, Sagamihara, Japan
🇯🇵
Yokohama City University Hospital, Kanagawa, Yokohama, Japan
🇯🇵
National Hospital Organization Yokohama Medical Center, Kanagawa, Yokohama, Japan

and more 42 locations

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