MedPath

Compugen

Ownership
-
Employees
68
Market Cap
-
Website
Introduction

Compugen Ltd. engages in the research, development, and commercialization of therapeutic and diagnostic biomarker product candidates including proteins and monoclonal antibodies. It focuses on research and development on immuno-oncology and autoimmune diseases. The company was founded by Eli Mintz, Simchon Faigler, and Amir Natan on February 10, 1993 and is headquartered in Holon, Israel.

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

Phase 1
Recruiting
Conditions
Ovarian Cancer
Ovarian Cancer Recurrent
Interventions
Drug: Normal Saline
First Posted Date
2025-03-21
Last Posted Date
2025-04-24
Lead Sponsor
Compugen Ltd
Target Recruit Count
60
Registration Number
NCT06888921
Locations
🇺🇸

West Cancer Center, Germantown, Tennessee, United States

A Clinical Trial to Assess COM503 in Participants with Advanced Solid Malignancies

Phase 1
Recruiting
Conditions
Neoplasm
Cancer, Malignant Tumors
Interventions
First Posted Date
2025-01-06
Last Posted Date
2025-01-15
Lead Sponsor
Compugen Ltd
Target Recruit Count
200
Registration Number
NCT06759649
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

NEXT Oncology San Antonio, San Antonio, Texas, United States

🇺🇸

START, San Antonio, Texas, United States

and more 1 locations

COM701 in Combination With BMS-986207 and Nivolumab in Subjects With Advanced Solid Tumors.

Phase 1
Completed
Conditions
Endometrial Neoplasms
Solid Tumor
Ovarian Cancer
Head and Neck Cancer
Interventions
Drug: COM701 in combination with BMS-986207 and nivolumab.
First Posted Date
2020-09-30
Last Posted Date
2024-07-18
Lead Sponsor
Compugen Ltd
Target Recruit Count
48
Registration Number
NCT04570839
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

The University of Tennessee WEST Cancer Center., Memphis, Tennessee, United States

and more 6 locations

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Phase 1
Recruiting
Conditions
HNSCC
MSS-CRC
Advanced Cancer
Lung Cancer
Ovarian Cancer
Colon Cancer
Multiple Myeloma
Microsatellite Stable Colorectal Carcinoma
Plasma Cell Neoplasm
First Posted Date
2020-04-21
Last Posted Date
2024-02-13
Lead Sponsor
Compugen Ltd
Target Recruit Count
110
Registration Number
NCT04354246
Locations
🇺🇸

Florida Cancer Specialists, Sarasota, Florida, United States

🇺🇸

Massachusetts General Hospital., Boston, Massachusetts, United States

🇺🇸

The Ohio State University Comprehensive Cancer Center., Columbus, Ohio, United States

and more 6 locations

COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.

Phase 1
Completed
Conditions
Advanced Cancer
Ovarian Cancer
Breast Cancer
Lung Cancer
Endometrial Cancer
Ovarian Neoplasm
Triple Negative Breast Cancer
Lung Neoplasm
Neoplasm Malignant
Colo-rectal Cancer
Interventions
Drug: COM701 with Opdivo (Nivolumab).
First Posted Date
2018-09-12
Last Posted Date
2025-01-17
Lead Sponsor
Compugen Ltd
Target Recruit Count
121
Registration Number
NCT03667716
Locations
🇺🇸

University of California Los Angeles (UCLA)., Los Angeles, California, United States

🇺🇸

M D Anderson Cancer Center., Houston, Texas, United States

🇺🇸

The START Center for Cancer Care., San Antonio, Texas, United States

and more 8 locations
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