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GENENTECH, INC.

GENENTECH, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1976-01-01
Employees
11.1K
Market Cap
-
Website
http://www.gene.com

A Study to Characterize Access to Specialty Care Received by American Indians/Alaska Natives

Completed
Conditions
Specialist Referral: Oncology
Specialist Referral: Neurology
Specialist Referral: Ophthalmology
Interventions
Other: No Intervention
First Posted Date
2022-11-22
Last Posted Date
2025-04-25
Lead Sponsor
Genentech, Inc.
Target Recruit Count
84
Registration Number
NCT05624788
Locations
🇺🇸

PPD Virtual - PPD - US, Wilmington, North Carolina, United States

🇺🇸

Avera Research Institute, Sioux Falls, South Dakota, United States

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1
Recruiting
Conditions
Locally Advanced or Metastatic Solid Tumors
NSCLC
HNSCC
Melanoma
TNBC
Esophageal Cancer
Gastric Cancer
Cervical Cancer
Colorectal Cancer
Urothelial Carcinoma
Interventions
First Posted Date
2022-10-14
Last Posted Date
2025-04-25
Lead Sponsor
Genentech, Inc.
Target Recruit Count
450
Registration Number
NCT05581004
Locations
🇳🇱

Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Netherlands

🇳🇱

Universitair Medisch Centrum Groningen, Groningen, Netherlands

🇺🇸

Florida Cancer Specialists - Sarasota, Sarasota, Florida, United States

and more 30 locations

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1
Active, not recruiting
Conditions
Advanced Solid Tumors
Metastatic Solid Tumors
Interventions
First Posted Date
2022-08-04
Last Posted Date
2025-03-25
Lead Sponsor
Genentech, Inc.
Target Recruit Count
232
Registration Number
NCT05487235
Locations
🇦🇷

Sanatorio Allende, Cordoba, Argentina

🇦🇷

Fundacion CORI para la Investigacion y Prevencion del Cancer, La Rioja, Argentina

🇦🇷

Centro Medico IPAM, Rosario, Argentina

and more 23 locations

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic Sclerosis

Phase 1
Active, not recruiting
Conditions
Systemic Sclerosis
Interventions
Drug: Placebo
First Posted Date
2022-07-18
Last Posted Date
2025-04-20
Lead Sponsor
Genentech, Inc.
Target Recruit Count
100
Registration Number
NCT05462522
Locations
🇫🇷

Centre Hospitalier Universitaire de Grenoble - Albert Michallon, La Tronche, France

🇫🇷

Hopital Cochin, Paris, France

🇫🇷

CHU de Bordeaux, Pessac, France

and more 21 locations

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Phase 3
Active, not recruiting
Conditions
Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Interventions
First Posted Date
2022-04-01
Last Posted Date
2025-04-15
Lead Sponsor
Genentech, Inc.
Target Recruit Count
320
Registration Number
NCT05306340
Locations
🇯🇵

Nagoya University Hospital, Aichi, Japan

🇿🇦

Medical Oncology Centre of Rosebank, Johannesburg, South Africa

🇪🇸

Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología, La Coruña, LA Coruna, Spain

and more 175 locations

An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration

Active, not recruiting
Conditions
Age-Related Macular Degeneration
Interventions
Other: No intervention
First Posted Date
2022-03-29
Last Posted Date
2025-04-08
Lead Sponsor
Genentech, Inc.
Target Recruit Count
400
Registration Number
NCT05300724
Locations
🇺🇸

Cleveland Clinic Cole Eye Institute, Cleveland, Ohio, United States

🇩🇪

Universitätsklinikum Bonn, Bonn, Germany

🇮🇱

Rabin Medical Center, Petach Tikva, Israel

and more 72 locations

A Study to Evaluate the Safety and Pharmacokinetics of XMAB24306 in Combination With Daratumumab in Participants With Relapsed/Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2022-02-17
Last Posted Date
2025-02-17
Lead Sponsor
Genentech, Inc.
Target Recruit Count
18
Registration Number
NCT05243342
Locations
🇳🇴

Oslo Universitetssykehus HF, Oslo, Norway

🇦🇺

Royal Adelaide Hospital, Adelaide, South Australia, Australia

🇦🇺

Alfred Hospital, Melbourne, Victoria, Australia

and more 4 locations

Long-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Phase 4
Active, not recruiting
Conditions
Spinal Muscular Atrophy
Interventions
Device: SMA-DAT Application and ADAM Sensor
First Posted Date
2022-02-10
Last Posted Date
2025-03-06
Lead Sponsor
Genentech, Inc.
Target Recruit Count
402
Registration Number
NCT05232929
Locations
🇺🇸

Barrow Neurological Institute, Phoenix, Arizona, United States

🇺🇸

Phoenix Children's Hospital, Phoenix, Arizona, United States

🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 36 locations

A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema

Phase 4
Active, not recruiting
Conditions
Diabetic Macular Edema
Interventions
First Posted Date
2022-02-04
Last Posted Date
2025-03-07
Lead Sponsor
Genentech, Inc.
Target Recruit Count
218
Registration Number
NCT05224102
Locations
🇺🇸

Scheie Eye Institute, Philadelphia, Pennsylvania, United States

🇺🇸

Barnet Dulaney Perkins Eye Center, Phoenix, Arizona, United States

🇺🇸

Win Retina, Arcadia, California, United States

and more 40 locations

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies

Phase 2
Active, not recruiting
Conditions
Non-Hodgkin Lymphoma
Interventions
First Posted Date
2022-01-26
Last Posted Date
2025-03-12
Lead Sponsor
Genentech, Inc.
Target Recruit Count
320
Registration Number
NCT05207670
Locations
🇺🇸

Texas Oncology (Tyler) - USOR, Tyler, Texas, United States

🇺🇸

Infirmary Cancer Care, Mobile, Alabama, United States

🇺🇸

Alaska Oncology & Hematology, LLC, Anchorage, Alaska, United States

and more 36 locations
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