DeepMed Research

Papworth Hospital

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension

Phase 2

Completed

Conditions: Pulmonary Arterial Hypertension

Interventions: Drug: Tocilizumab

First Posted Date: 2016-02-09

Last Posted Date: 2018-04-19

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 29

Registration Number: NCT02676947

Locations: 🇬🇧
Papworth Hospital NHS Foundation Trust, Cambridge, Cambridgeshire, United Kingdom

High Flow Nasal Oxygen Therapy (Optiflow™) in High-risk Cardiac Surgical Patients

Not Applicable

Completed

Conditions: Cardiac Surgery

Interventions: Device: High flow nasal oxygen therapy (Optiflow™)
Device: Standard oxygen therapy (Hudson Type face mask or nasal prongs)

First Posted Date: 2015-07-14

Last Posted Date: 2017-12-02

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 100

Registration Number: NCT02496923

Locations: 🇬🇧
Department of Cardiothoracic Anaesthesia and Critical Care Medicine, Papworth Hospital NHS Foundation Trust, Cambridge, Cambridgeshire, United Kingdom

3D Echocardiographic Assessment of RV Function in Patients Undergoing Pulmonary Endarterectomy

Conditions: Chronic Thromboembolic Pulmonary Hypertension

Interventions: Procedure: Pulmonary endarterectomy

First Posted Date: 2015-04-24

Last Posted Date: 2015-04-28

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 51

Registration Number: NCT02426203

Home Monitoring to Predict Exacerbation in Cystic Fibrosis

Completed

Conditions: Cystic Fibrosis

First Posted Date: 2015-04-15

Last Posted Date: 2021-03-16

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 147

Registration Number: NCT02416375

Locations: 🇬🇧
Papworth Hospital NHS Trust, Cambridge, United Kingdom

Prospective Identification of High-risk Coronary Plaques Through Non-invasive Imaging

Conditions: Coronary Plaques

Interventions: Other: Telephone interview

First Posted Date: 2015-01-27

Last Posted Date: 2015-01-27

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 100

Registration Number: NCT02347306

Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting

Not Applicable

Conditions: Right Ventricular Diastolic Dysfunction
Right Coronary Artery Percutaneous Coronary Intervention

Interventions: Procedure: Right Coronary Artery Percutaneous Coronary Intervention
Other: saline placebo infusion
Other: GLP-1 Infusion

First Posted Date: 2014-09-10

Last Posted Date: 2016-04-11

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 30

Registration Number: NCT02236299

Locations: 🇬🇧
Papworth Hospital NHS Foundation Turst, Cambridge, Cambridgeshire, United Kingdom

The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure

Phase 1

Completed

Conditions: Heart Failure

Interventions: Drug: Glucagon-Like Peptide 1

First Posted Date: 2014-05-02

Last Posted Date: 2018-04-05

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 10

Registration Number: NCT02129179

Locations: 🇬🇧
Papworth Hospital NHS Foundation Trust, Papworth Everard, United Kingdom

Cardioprotective Effects of GLP-1 and Their Mechanisms

Phase 1

Completed

Conditions: Angina Pectoris

Interventions: Drug: GLP-1 (7-36) amide
Drug: Glibenclamide

First Posted Date: 2014-05-01

Last Posted Date: 2016-04-11

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 32

Registration Number: NCT02128022

Locations: 🇬🇧
Papworth Hospital, Cambridge, Cambridgeshire, United Kingdom

GLP-1 Loading During Elective Percutaneous Coronary Intervention

Phase 2

Conditions: Angina Pectoris
Myocardial Infarction
Reperfusion Injury
Coronary Heart Disease

Interventions: Drug: placebo
Drug: GLP-1

First Posted Date: 2014-05-01

Last Posted Date: 2018-06-06

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 193

Registration Number: NCT02127996

Locations: 🇬🇧
Papworth Hospital, Cambridge, Cambridgeshire, United Kingdom

Feasibility Study of Preoperative Cognitive Training in Cardiac Surgical Patients

Not Applicable

Conditions: Postoperative Cognitive Dysfunction

Interventions: Behavioral: Cog-Train Intervention

First Posted Date: 2014-02-03

Last Posted Date: 2017-12-02

Lead Sponsor: Papworth Hospital NHS Foundation Trust

Target Recruit Count: 10

Registration Number: NCT02053207

Locations: 🇬🇧
Papworth Hospital NHS Foundation Trust, Cambridge, Cambridgeshire, United Kingdom

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