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M.D. ANDERSON CANCER CENTER

🇺🇸United States
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Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

Phase 1
Recruiting
Conditions
Myxoid/Round Cell Liposarcoma
Synovial Sarcoma
Interventions
First Posted Date
2023-10-16
Last Posted Date
2025-04-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
44
Registration Number
NCT06083883
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

Phase 1
Recruiting
Conditions
Ovarian Clear Cell Carcinoma
Interventions
First Posted Date
2023-10-04
Last Posted Date
2025-05-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
21
Registration Number
NCT06065462
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial

Phase 1
Recruiting
Conditions
Prostate Cancer
First Posted Date
2023-10-04
Last Posted Date
2025-04-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
36
Registration Number
NCT06066437
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Phase 1
Recruiting
Conditions
Solid Tumors
Interventions
First Posted Date
2023-10-04
Last Posted Date
2025-04-24
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
54
Registration Number
NCT06066424
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases

Phase 3
Recruiting
Conditions
Bone Metastases
Interventions
Drug: Radiation Therapy
First Posted Date
2023-10-04
Last Posted Date
2025-03-25
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
220
Registration Number
NCT06065449
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma

First Posted Date
2023-10-04
Last Posted Date
2025-06-04
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
44
Registration Number
NCT06066359
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

Phase 2
Recruiting
Conditions
Renal Cell Carcinoma
Interventions
First Posted Date
2023-09-26
Last Posted Date
2025-03-05
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
48
Registration Number
NCT06053658
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell Carcinoma

Phase 2
Terminated
Conditions
Head Neck
Squamous Cell Carcinoma of Head and Neck
Interventions
First Posted Date
2023-09-21
Last Posted Date
2024-10-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
57
Registration Number
NCT06046482
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Immunogenicity and Clinical Efficacy of 20-valent Pneumococcal Conjugate Vaccine (PCV20) in Lymphoma Survivors After Treatment With Anti-CD20 Therapy

Phase 4
Recruiting
Conditions
Lymphoma
Interventions
First Posted Date
2023-09-21
Last Posted Date
2025-05-14
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
30
Registration Number
NCT06049134
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma

Phase 2
Recruiting
Conditions
Large B-cell Lymphoma
Interventions
First Posted Date
2023-09-21
Last Posted Date
2025-03-10
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT06045247
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

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