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M.D. ANDERSON CANCER CENTER

🇺🇸United States
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Gallium-68 PSMA-11 PET in Participants With Prostate Cancer

Phase 2
Withdrawn
Conditions
Recurrent Prostate Carcinoma
Stage IV Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Metastatic Prostate Carcinoma
Stage IVA Prostate Cancer AJCC v8
Interventions
Procedure: Computed Tomography
Drug: Gallium Ga 68-labeled PSMA-11
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
First Posted Date
2021-09-05
Last Posted Date
2024-03-07
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT05034562

Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors

Early Phase 1
Recruiting
Conditions
Myeloid Leukemia
Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Interventions
Procedure: Biopsy
Procedure: Biospecimen Collection
Other: Electronic Health Record Review
Other: Photography
First Posted Date
2021-09-05
Last Posted Date
2024-10-21
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
10
Registration Number
NCT05035706
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Phase 2
Recruiting
Conditions
Breast Cancer
HER2-positive
Interventions
First Posted Date
2021-09-05
Last Posted Date
2025-01-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
20
Registration Number
NCT05035836
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Phase 1
Active, not recruiting
Conditions
Recurrent B Acute Lymphoblastic Leukemia
Refractory Lymphoblastic Lymphoma
Refractory B Acute Lymphoblastic Leukemia
Recurrent Adult Lymphoblastic Lymphoma
Refractory T Acute Lymphoblastic Leukemia
Recurrent T Acute Lymphoblastic Leukemia
Interventions
First Posted Date
2021-09-02
Last Posted Date
2024-10-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
4
Registration Number
NCT05032183
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents

Phase 1
Completed
Conditions
Refractory Myelodysplastic Syndrome
Refractory Chronic Myelomonocytic Leukemia
Interventions
First Posted Date
2021-09-01
Last Posted Date
2024-12-12
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
11
Registration Number
NCT05030675
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Feasibility of Digital Thermal Monitoring to Assess Endothelium-Dependent Vasodilation in Patients Undergoing Hematopoietic Cell Transplantation (HCT)

Not Applicable
Recruiting
Conditions
Vascular
Endothelial
Endothelix
Endothelial Dysfunction
Interventions
Device: Vendys II Device
First Posted Date
2021-09-01
Last Posted Date
2024-12-04
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
50
Registration Number
NCT05029752
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)

Phase 2
Recruiting
Conditions
the Nasal Cavity
Paranasal Sinuses
Squamous Cell Carcinoma
Interventions
First Posted Date
2021-08-30
Last Posted Date
2024-12-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
35
Registration Number
NCT05027633
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Sintilimab for the Treatment of Locally Advanced, Metastatic, or Recurrent Angiosarcoma, the SiARa Cancer Study

Phase 2
Active, not recruiting
Conditions
Metastatic Angiosarcoma
Recurrent Angiosarcoma
Locally Advanced Angiosarcoma
Interventions
Other: Quality-of-Life Assessment
Biological: Sintilimab
First Posted Date
2021-08-30
Last Posted Date
2024-11-11
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
6
Registration Number
NCT05026736
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases

Phase 2
Recruiting
Conditions
Metastatic Melanoma
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Interventions
Drug: Binimetinib
Drug: Encorafenib
Other: Questionnaire Administration
First Posted Date
2021-08-30
Last Posted Date
2024-07-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
35
Registration Number
NCT05026983
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma

Phase 1
Recruiting
Conditions
Ann Arbor Stage III Marginal Zone Lymphoma
Refractory Follicular Lymphoma
Ann Arbor Stage III Grade 3 Follicular Lymphoma
Refractory High Grade B-Cell Lymphoma
Refractory Mantle Cell Lymphoma
Ann Arbor Stage III Grade 2 Follicular Lymphoma
Ann Arbor Stage IV Grade 3 Follicular Lymphoma
Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Aggressive B-Cell Non-Hodgkin Lymphoma
Interventions
Drug: CD47 Antagonist ALX148
Drug: Lenalidomide
Biological: Rituximab
First Posted Date
2021-08-27
Last Posted Date
2024-10-30
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
47
Registration Number
NCT05025800
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

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