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M.D. ANDERSON CANCER CENTER

🇺🇸United States
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Nivolumab, Ipilimumab and Chemoradiation in Treating Patients with Resectable Gastric Cancer

Phase 2
Active, not recruiting
Conditions
Clinical Stage 0 Gastric Cancer AJCC V8
Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC V8
Clinical Stage IIB Gastric Cancer AJCC V8
Clinical Stage I Gastric Cancer AJCC V8
Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC V8
Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC V8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC V8
Clinical Stage IVA Gastric Cancer AJCC V8
Gastric Adenocarcinoma
Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC V8
Interventions
Drug: Fluorouracil
Radiation: Intensity-Modulated Radiation Therapy
Biological: Ipilimumab
Biological: Nivolumab
Drug: Oxaliplatin
Procedure: Therapeutic Conventional Surgery
First Posted Date
2018-12-14
Last Posted Date
2024-11-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
32
Registration Number
NCT03776487
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct Disorders

Not Applicable
Completed
Conditions
Bile Duct Disorder
Endocrine Pancreas Disorder
Interventions
Procedure: Endoscopic Retrograde Cholangiopancreatography
Other: Interview
Device: Laryngeal Mask Airway
First Posted Date
2018-12-14
Last Posted Date
2021-04-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
33
Registration Number
NCT03775681
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

Phase 1
Completed
Conditions
Anatomic Stage IIIB Breast Cancer AJCC v8
Anatomic Stage IIIC Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Prognostic Stage I Breast Cancer AJCC v8
Prognostic Stage IA Breast Cancer AJCC v8
Prognostic Stage IIA Breast Cancer AJCC v8
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Prognostic Stage IIIA Breast Cancer AJCC v8
Prognostic Stage IIIB Breast Cancer AJCC v8
Interventions
First Posted Date
2018-12-13
Last Posted Date
2024-04-19
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
15
Registration Number
NCT03774472
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients with Prostate Cancer

Phase 2
Recruiting
Conditions
Prostate Carcinoma
Interventions
Behavioral: Exercise Intervention
Other: Quality-of-Life Assessment
Other: Placebo
Drug: Methylphenidate
Other: Questionnaire Administration
Other: Stretching
First Posted Date
2018-12-11
Last Posted Date
2024-10-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
200
Registration Number
NCT03772834
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Nivolumab and Ibrutinib in Treating Patients With Relapsed or Refractory Central Nervous System Lymphoma

Phase 2
Active, not recruiting
Conditions
Recurrent Central Nervous System Lymphoma
Refractory Central Nervous System Lymphoma
Central Nervous System B-Cell Non-Hodgkin Lymphoma
Interventions
First Posted Date
2018-12-10
Last Posted Date
2024-10-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
18
Registration Number
NCT03770416
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Daratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Phase 2
Active, not recruiting
Conditions
Refractory Plasma Cell Myeloma
Recurrent Plasma Cell Myeloma
Interventions
First Posted Date
2018-12-04
Last Posted Date
2024-12-17
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
40
Registration Number
NCT03763162
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

TAK-659 and Paclitaxel in Treating Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Malignant Solid Neoplasm
Ovarian Carcinoma
Refractory Malignant Solid Neoplasm
Refractory Ovarian Carcinoma
Interventions
Drug: Mivavotinib
Drug: Paclitaxel
Other: Pharmacokinetic Study
First Posted Date
2018-11-28
Last Posted Date
2023-02-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
52
Registration Number
NCT03756818
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before Surgery

Not Applicable
Recruiting
Conditions
Head and Neck Neoplasm
Interventions
Procedure: Tracheal Intubation
Device: Laryngoscopy
First Posted Date
2018-11-28
Last Posted Date
2024-04-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
120
Registration Number
NCT03757091
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

Phase 1
Recruiting
Conditions
Anaplastic Ependymoma
Ependymoma
Interventions
Radiation: Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
First Posted Date
2018-11-23
Last Posted Date
2024-11-13
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
48
Registration Number
NCT03750513
Locations
🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

TK216 and Decitabine in Treating Patients With Relapsed and Refractory Acute Myeloid Leukemia

Phase 1
Withdrawn
Conditions
Refractory Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Interventions
Drug: Expansion Phase TK216
Drug: Expansion Phase Decitabine
First Posted Date
2018-11-23
Last Posted Date
2019-05-06
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT03752138
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