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AVROBIO, INC.

AVROBIO, INC. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2015-01-01
Employees
101
Market Cap
$5.2M
Website
http://tectonictx.com

Clinical Trials

5

Active:0
Completed:0

Trial Phases

2 Phases

Phase 1:2
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (3 trials with phase data)• Click on a phase to view related trials

Phase 1
2 (66.7%)
Phase 2
1 (33.3%)

An Efficacy and Safety Study of AVR-RD-02 Compared to Enzyme Replacement Therapy for Treatment of Gaucher Disease Type 3

Phase 2
Withdrawn
Conditions
Gaucher Disease, Type 3
Interventions
Drug: Gene therapy
Drug: Enzyme Replacement Agent
First Posted Date
2023-04-18
Last Posted Date
2023-08-09
Lead Sponsor
AVROBIO
Registration Number
NCT05815004

Long-Term Follow-up Study of Subjects With Fabry Disease Who Received Lentiviral Gene Therapy in Study AVRO-RD-01-201

Terminated
Conditions
Fabry Disease
First Posted Date
2021-08-10
Last Posted Date
2023-08-31
Lead Sponsor
AVROBIO
Target Recruit Count
5
Registration Number
NCT04999059
Locations
🇦🇺

Royal Melbourne Hospital, Melbourne, Parkville VIC, Australia

🇦🇺

Royal Perth Hospital, Perth, Australia

🇧🇷

Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil

A Long-Term Follow-up Study of Subjects With Gaucher Disease Who Previously Received AVR-RD-02

Terminated
Conditions
Type 1 Gaucher Disease
First Posted Date
2021-04-08
Last Posted Date
2023-08-29
Lead Sponsor
AVROBIO
Target Recruit Count
4
Registration Number
NCT04836377
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇨🇦

M.A.G.I.C. Clinic Ltd, Calgary, Calgary Alberta, Canada

Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease

Phase 1
Terminated
Conditions
Gaucher Disease
Interventions
First Posted Date
2019-10-30
Last Posted Date
2024-01-18
Lead Sponsor
AVROBIO
Target Recruit Count
8
Registration Number
NCT04145037
Locations
🇺🇸

University of California San Diego, San Diego, California, United States

🇺🇸

University of Iowa, Iowa City, Iowa, United States

🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

and more 2 locations

Open Label, Study Of Efficacy and Safety Of AVR-RD-01 for Treatment-Naive Subjects With Classic Fabry Disease

Phase 1
Terminated
Conditions
Fabry Disease
Interventions
First Posted Date
2018-03-06
Last Posted Date
2024-01-05
Lead Sponsor
AVROBIO
Target Recruit Count
15
Registration Number
NCT03454893
Locations
🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

🇦🇺

Royal Melbourne Hospital, Melbourne, Parkville VIC, Australia

and more 2 locations

News

Advancements in Pompe Disease Treatment: A Pipeline Review

• Pompe disease, a rare genetic disorder, is seeing advancements with over 20 therapies in the pipeline. • Key players like Amicus Therapeutics and Spark Therapeutics are developing novel treatments, including gene therapies and enzyme replacements. • Clinical trials are underway, evaluating the safety and efficacy of drugs like Cipaglucosidase alfa and SPK-3006. • These emerging therapies target various mechanisms, such as alpha-glucosidase replacement and glycogen synthase kinase modulation.

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