The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
- Conditions
- Relapsing Remitting Multiple Sclerosis
- Interventions
- Drug: Disease-Modifying Therapies (DMTs)
- First Posted Date
- 2025-01-28
- Last Posted Date
- 2025-01-28
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 60
- Registration Number
- NCT06796504
Long Term Extension of Safety and Efficacy of Vagus Nerve Stimulator in Patients With Rheumatoid Arthritis (RA)
- Conditions
- Rheumatoid Arthritis
- Interventions
- Device: SetPoint Medical Neurostimulation of the Cholinergic Anti-inflammatory Pathway System
- First Posted Date
- 2021-04-27
- Last Posted Date
- 2025-05-13
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 14
- Registration Number
- NCT04862117
- Locations
- 🇺🇸
Florida Medical Clinic, PA, Zephyrhills, Florida, United States
🇺🇸Arthritis & Rheumatic Disease Specialties, Aventura, Florida, United States
🇺🇸Northwell Health, Great Neck, New York, United States
Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis
- Conditions
- Rheumatoid Arthritis
- Interventions
- Procedure: Implant ProcedureDrug: Conventional Synthetic DMARDDevice: Active stimulationDevice: Non-active stimulation
- First Posted Date
- 2020-09-07
- Last Posted Date
- 2025-01-13
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 243
- Registration Number
- NCT04539964
- Locations
- 🇺🇸
Willow Rheumatology and Wellness PLLC, Willowbrook, Illinois, United States
🇺🇸Arizona Arthritis ans Rheumatology Research, PPLC, Mesa, Arizona, United States
🇺🇸Arizona Arthritis Rheumatology & Research, PLLC, Phoenix, Arizona, United States
Safety and Efficacy of Vagus Nerve Stimulator in Patients With Rheumatoid Arthritis (RA)
- Conditions
- Rheumatoid Arthritis
- Interventions
- Device: SetPoint Medical Neurostimulation of the Cholinergic Anti-inflammatory Pathway System
- First Posted Date
- 2018-02-19
- Last Posted Date
- 2018-12-27
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 14
- Registration Number
- NCT03437473
- Locations
- 🇺🇸
Altoona Center for Clinical Research, Duncansville, Pennsylvania, United States
🇺🇸Arthritis & Rheumatic Disease Specialties, Aventura, Florida, United States
🇺🇸Florida Medical Clinic, P.A., Zephyrhills, Florida, United States
Long Term Observational Study of a Vagal Nerve Stimulation Device in Crohn's Disease
- Conditions
- Crohn Disease
- Interventions
- Device: Cyberonics VNS
- First Posted Date
- 2016-11-01
- Last Posted Date
- 2017-08-03
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 15
- Registration Number
- NCT02951650
- Locations
- 🇭🇷
Dubrava Hospital, Zagreb, Croatia
🇳🇱Academic Medical Center, Amsterdam, Netherlands
🇸🇪Karolinska Institute, Stockholm, Sweden
Vagus Nerve Stimulation in Crohn's Disease
- Conditions
- Crohn's Disease
- Interventions
- Device: Vagus Nerve Stimulation Device
- First Posted Date
- 2014-12-08
- Last Posted Date
- 2017-08-03
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 15
- Registration Number
- NCT02311660
- Locations
- 🇭🇷
Clinical Hospital Dubrava, Zagreb, Croatia
🇮🇹Humanitas Research Hospital, Milano, Italy
🇸🇪Karolinska University Hospital, Solna, Stockholm, Sweden
Long Term Extension Study For SPM-005 Participants
- Conditions
- Rheumatoid Arthritis
- Interventions
- Device: Cyberonics VNS System
- First Posted Date
- 2012-03-13
- Last Posted Date
- 2016-11-01
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 18
- Registration Number
- NCT01552538
- Locations
- 🇧🇦
Sveučilišna klinička bolnica Mostar, Mostar, Bosnia and Herzegovina
🇧🇦Klinicki Centar Univerziteta, Reumatologija, Sarajevo, Bosnia and Herzegovina
🇭🇷Sisters of Mercy Clinical Hospital Centre, Zagreb, Croatia
Safety and Efficacy Vagal Nerve Stimulation in Patients With Rheumatoid Arthritis
- Conditions
- Rheumatoid Arthritis
- Interventions
- Device: Cyberonics VNS System
- First Posted Date
- 2012-03-13
- Last Posted Date
- 2016-11-01
- Lead Sponsor
- SetPoint Medical Corporation
- Target Recruit Count
- 18
- Registration Number
- NCT01552941
- Locations
- 🇳🇱
Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
🇧🇦Sveučilišna klinička bolnica Mostar, Mostar, Bosnia and Herzegovina
🇧🇦Klinicki Centar Univerziteta, Reumatologija, Sarajevo, Bosnia and Herzegovina