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BAVARIAN NORDIC

🇩🇰Denmark

Country: 🇩🇰Denmark

Ownership: -

Established: 1992-01-01

Employees: 759

Market Cap: $3.1B

Website: http://www.bavarian-nordic.com

Clinical Trials

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

Phase 2

Completed

Conditions: RSV Infection

Interventions: Biological: MVA-mBN294B
Drug: Placebo

First Posted Date: 2021-02-12

Last Posted Date: 2023-07-21

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 73

Registration Number: NCT04752644

Locations: 🇬🇧
hVIVO Services Limited, London, United Kingdom

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

Phase 1

Completed

Conditions: Chordoma
HER2-positive Breast Cancer

Interventions: Biological: TAEK-VAC-HerBy

First Posted Date: 2020-01-29

Last Posted Date: 2025-03-03

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 37

Registration Number: NCT04246671

Locations: 🇺🇸
Mayo Clinic - Phoenix, Scottsdale, Arizona, United States
🇺🇸
Providence Saint John's Health Center, Santa Monica, California, United States
🇺🇸
Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

and more 6 locations

A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer

Phase 1

Completed

Conditions: Solid Metastatic Tumor

Interventions: Biological: MVA-BN-Brachyury

First Posted Date: 2019-10-22

Last Posted Date: 2021-07-14

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 13

Registration Number: NCT04134312

Locations: 🇺🇸
National Cancer Institute, Bethesda, Maryland, United States

Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects

Phase 1

Completed

Conditions: Equine Encephalitis

Interventions: Biological: MVA-BN-WEV Dose 1
Biological: MVA-BN-WEV Dose 3
Biological: MVA-BN-WEV Dose 2

First Posted Date: 2019-10-18

Last Posted Date: 2020-08-20

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 45

Registration Number: NCT04131595

Locations: 🇺🇸
Johnson County Clin-Trials, Lenexa, Kansas, United States

Phase 2 Open-label Study of Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317)

Phase 2

Completed

Conditions: Chikungunya

Interventions: Biological: Chikungunya

First Posted Date: 2019-06-20

Last Posted Date: 2024-10-16

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 60

Registration Number: NCT03992872

Locations: 🇺🇸
United States Army Medical Research Institute of Infectious Diseases, Fort Deterick, Maryland, United States
🇺🇸
Walter Reed Army Institute of Research, Silver Spring, Maryland, United States

Freeze-Dried MVA-BN® Lot Consistency Smallpox Trial

Phase 3

Completed

Conditions: Smallpox

Interventions: Biological: FD MVA-BN

First Posted Date: 2018-10-09

Last Posted Date: 2021-05-27

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 1129

Registration Number: NCT03699124

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Optimal Research, LLC (Synexus), Rockville, Maryland, United States
🇺🇸
University of Iowa, Iowa City, Iowa, United States

and more 7 locations

CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

Phase 2

Completed

Conditions: Bladder Cancer

Interventions: Biological: CV301
Biological: Atezolizumab

First Posted Date: 2018-08-14

Last Posted Date: 2022-04-27

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 43

Registration Number: NCT03628716

Locations: 🇺🇸
H. Lee Moffitt Cancer Center & Research Institute, Inc., Tampa, Florida, United States
🇺🇸
Norton Cancer Institute, Norton Healthcare Pavilion, Louisville, Kentucky, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 3 locations

BN Brachyury and Radiation in Chordoma

Phase 2

Completed

Conditions: Chordoma

Interventions: Biological: BN-Brachyury plus radiation

First Posted Date: 2018-07-23

Last Posted Date: 2023-04-14

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 29

Registration Number: NCT03595228

Locations: 🇺🇸
Mayo Clinic, Arizona, Phoenix, Arizona, United States
🇺🇸
Mayo Clinic, Florida, Jacksonville, Florida, United States
🇺🇸
Massachusetts General Hospital, Cancer Center, Boston, Massachusetts, United States

and more 2 locations

Trial of a Chikungunya Vaccine, PXVX0317 CHIKV-VLP, in Healthy Adults

Phase 2

Completed

Conditions: Chikungunya Virus Infection

Interventions: Biological: CHIKV VLP/unadjuvanted
Biological: CHIKV VLP/adjuvanted
Biological: Placebo

First Posted Date: 2018-03-30

Last Posted Date: 2023-07-03

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 445

Registration Number: NCT03483961

Locations: 🇺🇸
Johnson County Clin-Trials, Lenexa, Kansas, United States
🇺🇸
The Center for Pharmaceutical Research, Kansas City, Missouri, United States
🇺🇸
Advanced Clinical Research, West Jordan, Utah, United States

Special Access Program IMVAMUNE®

Phase 4

Completed

Conditions: Vaccination

Interventions: Biological: IMVAMUNE®

First Posted Date: 2018-03-21

Last Posted Date: 2020-08-19

Lead Sponsor: Bavarian Nordic

Target Recruit Count: 22

Registration Number: NCT03472014

Locations: 🇺🇸
Palo Alto Medical Foundation, Palo Alto, California, United States

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