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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Romosozumab (AMG 785) in Postmenopausal Women With Low Bone Mineral Density

Phase 2
Completed
Conditions
Low Bone Mineral Density
Postmenopausal Osteoporosis
Interventions
First Posted Date
2009-05-11
Last Posted Date
2022-09-22
Lead Sponsor
Amgen
Target Recruit Count
419
Registration Number
NCT00896532

A High-resolution Peripheral Quantitative Computed Tomography Study in Postmenopausal Women Previously Treated With Denosumab

Phase 3
Completed
Conditions
Low Bone Mass
Low Bone Mineral Density
Postmenopausal Osteoporosis
Osteoporosis
Interventions
Procedure: high-resolution peripheral quantitative computed tomography (HR-pQCT)
Procedure: Dual energy X-ray absorptiometry (DXA)
Biological: Denosumab
Drug: Placebo
First Posted Date
2009-04-30
Last Posted Date
2014-04-02
Lead Sponsor
Amgen
Target Recruit Count
79
Registration Number
NCT00890981

A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab

Phase 2
Completed
Conditions
Low Bone Mineral Density
Osteoporosis
Postmenopausal Osteoporosis
Low Bone Mass
Interventions
First Posted Date
2009-04-24
Last Posted Date
2013-11-15
Lead Sponsor
Amgen
Target Recruit Count
15
Registration Number
NCT00887965

A Study of Extended Carfilzomib Therapy for Patients Previously Enrolled in Carfilzomib Treatment Protocols

Phase 2
Completed
Conditions
Multiple Myeloma
Solid Tumors
Interventions
First Posted Date
2009-04-20
Last Posted Date
2018-05-14
Lead Sponsor
Amgen
Target Recruit Count
101
Registration Number
NCT00884312
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

The Cleveland Clinic Foundation, Cleveland, Ohio, United States

🇺🇸

University of Maryland, Greenebaum Cancer Center, Baltimore, Maryland, United States

and more 20 locations

A Study of Neutropenia and Anemia Management in Patients With Solid Tumors Receiving Myelotoxic Chemotherapy

Completed
Conditions
Ovarian Cancer
Non-Small Cell Lung Cancer
Breast Cancer
Small Cell Lung Cancer
First Posted Date
2009-04-17
Last Posted Date
2017-03-15
Lead Sponsor
Amgen
Target Recruit Count
1370
Registration Number
NCT00883181

Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis

Phase 1
Completed
Conditions
Cystinosis
Interventions
First Posted Date
2009-03-31
Last Posted Date
2024-12-19
Lead Sponsor
Amgen
Target Recruit Count
9
Registration Number
NCT00872729
Locations
🇺🇸

University of California San Diego Medical Center, San Diego, California, United States

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Phase 2
Completed
Conditions
Inoperable Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Interventions
First Posted Date
2009-03-30
Last Posted Date
2016-04-04
Lead Sponsor
Amgen
Target Recruit Count
60
Registration Number
NCT00872014

A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease

Phase 2
Completed
Conditions
Behcet Syndrome
Interventions
First Posted Date
2009-03-20
Last Posted Date
2020-06-19
Lead Sponsor
Amgen
Target Recruit Count
111
Registration Number
NCT00866359
Locations
🇹🇷

Selçuk University, Konya, Turkey

🇺🇸

Mayo Clinic - Rheumatology and Internal Medicine, Jacksonville, Florida, United States

🇺🇸

Cleveland Clinic Foundation, Cleveland, Ohio, United States

and more 4 locations

Effects of Long-term Dosing of AMG 531 on Bone Marrow Morphology

Completed
Conditions
Idiopathic Thrombocytopenic Purpura
Interventions
Other: No Intervention for Observational Study
First Posted Date
2009-03-13
Last Posted Date
2010-07-16
Lead Sponsor
Amgen
Target Recruit Count
10
Registration Number
NCT00861224

To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.

Phase 1
Completed
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2009-03-13
Last Posted Date
2017-02-08
Lead Sponsor
Amgen
Target Recruit Count
88
Registration Number
NCT00861419
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