MedPath

ARBUTUS BIOPHARMA INC

ARBUTUS BIOPHARMA INC logo
🇺🇸United States
Ownership
-
Employees
-
Market Cap
-
Website

Clinical Trials

21

Active:6
Completed:4

Trial Phases

2 Phases

Phase 1:17
Phase 2:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (20 trials with phase data)• Click on a phase to view related trials

Phase 1
17 (85.0%)
Phase 2
3 (15.0%)

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Recruiting
Conditions
Long Term Follow-up
First Posted Date
2024-02-26
Last Posted Date
2024-11-27
Lead Sponsor
Arbutus Biopharma Corporation
Target Recruit Count
50
Registration Number
NCT06277037
Locations
🇺🇸

Research and Education Inc., San Diego, California, United States

🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

🇺🇸

Infectious Disease Care, Hillsborough, New Jersey, United States

and more 15 locations

Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection

Phase 2
Withdrawn
Conditions
Hepatitis B, Chronic
Interventions
First Posted Date
2024-02-07
Last Posted Date
2024-08-12
Lead Sponsor
Arbutus Biopharma Corporation
Registration Number
NCT06245291
Locations
🇬🇪

Infectious Diseases, AIDS and Clinical Immunology Research Center, Tbilisi, Georgia

🇬🇪

LLC "Neolab", Tbilisi, Georgia

🇭🇰

Prince Of Wales Hospital - The Chinese University Of Hong Kong, Hong Kong, Hong Kong

and more 18 locations

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AB-101 Following Oral Administration in Healthy and Chronic Hepatitis B Subjects

Phase 1
Active, not recruiting
Conditions
Chronic hepatitis B virus Infection
Interventions
Drug: Placebo
Drug: Nucleos(t)ide Analogue
First Posted Date
2024-12-04
Last Posted Date
2025-04-02
Lead Sponsor
Arbutus Biopharma Inc.
Target Recruit Count
27
Registration Number
2023-508312-39-00
Locations
🇧🇬

Umbal - Prof. D-R Stoyan Kirkovich AD, Stara Zagora, Bulgaria

🇧🇬

Military Medical Academy, Sofiya, Bulgaria

🇮🇹

Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy

and more 2 locations

Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection

Phase 2
Active, not recruiting
Conditions
Chronic Hepatitis b
Interventions
Drug: Peg-IFNα-2a
First Posted Date
2021-07-28
Last Posted Date
2025-05-08
Lead Sponsor
Arbutus Biopharma Corporation
Target Recruit Count
43
Registration Number
NCT04980482
Locations
🇺🇸

Arizona Liver Health, Tucson, Arizona, United States

🇺🇸

Research and Education, Inc., San Diego, California, United States

🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

and more 13 locations

Safety, Tolerability, and Pharmacokinetics of AB-836 in Healthy Subjects and Subjects With Chronic HBV Infection

Phase 1
Terminated
Conditions
Chronic Hepatitis
Interventions
Drug: Placebo
Drug: Nucleos(t)ide Analogue
First Posted Date
2021-03-01
Last Posted Date
2022-11-21
Lead Sponsor
Arbutus Biopharma Corporation
Target Recruit Count
110
Registration Number
NCT04775797
Locations
🇦🇺

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

🇦🇺

Nepean Hospital, Kingswood, New South Wales, Australia

🇨🇦

Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

and more 12 locations
  • Prev
  • 1
  • 2
  • 3
  • Next

News

Arbutus Reacquires Global Rights to Hepatitis B RNAi Therapy After Achieving Functional Cure in Eight Patients

Arbutus Biopharma has reacquired Greater China rights to imdusiran from Qilu Pharmaceutical, regaining global control of the hepatitis B RNAi therapeutic.

Imdusiran, VTP-300, and Nivolumab Combination Shows Promise in Chronic Hepatitis B

A Phase 2a trial shows that imdusiran, VTP-300, and low-dose nivolumab led to significantly greater HBsAg declines in chronic hepatitis B patients.

© Copyright 2025. All Rights Reserved by MedPath