DeepMed Research

UNIVERSITY COLLEGE LONDON

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1826-02-11

Employees: 10K

Market Cap: -

Website: http://www.ucl.ac.uk

Clinical Trials

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

Phase 1

Not yet recruiting

Conditions: Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)
Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)
Alzheimer Disease

Interventions: Drug: NIO752
Other: Placebo

First Posted Date: 2024-04-18

Last Posted Date: 2024-04-18

Lead Sponsor: University College, London

Target Recruit Count: 10

Registration Number: NCT06372821

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer

Phase 3

Recruiting

Conditions: Prostate Cancer Metastatic

Interventions: Radiation: Stereotactic Ablative Body Radiotherapy (SABR)
Drug: Androgen Deprivation Therapy (ADT)
Other: 177Lu-PSMA-617
Drug: Niraparib and Abiraterone Acetate Dual Action Tablet DAT
Drug: Apalutamide
Drug: Androgen Receptor Signalling Inhibitor (ARSI)
Drug: Abiraterone Acetate
Radiation: Local Radiotherapy
Drug: Docetaxel
Drug: Prednisolone

First Posted Date: 2024-03-20

Last Posted Date: 2024-08-09

Lead Sponsor: University College, London

Target Recruit Count: 8000

Registration Number: NCT06320067

Locations: 🇬🇧
University College London Hospitals NHS Foundation Trust, London, United Kingdom
🇬🇧
The Royal Marsden Hospital, Sutton, United Kingdom
🇬🇧
Royal Devon University Hospital Trust, Exeter, United Kingdom

Feasibility of Proteomics in Chronic Lung Disease With Sarcopenia

Not yet recruiting

Conditions: Sarcopenia
Chronic Lung Disease

Interventions: Other: This is observational study

First Posted Date: 2024-03-15

Last Posted Date: 2024-03-15

Lead Sponsor: University College, London

Target Recruit Count: 49

Registration Number: NCT06312774

Red Light Ptosis Proof-of-Concept

Not Applicable

Recruiting

Conditions: Mitochondrial Diseases
Blepharoptosis

Interventions: Device: Near-infrared light

First Posted Date: 2024-03-05

Last Posted Date: 2024-03-05

Lead Sponsor: University College, London

Target Recruit Count: 10

Registration Number: NCT06292182

Locations: 🇬🇧
Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom

Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study

Recruiting

Conditions: Dentatorubral-Pallidoluysian Atrophy

Interventions: Other: Positive genetic test for pathological expansion in ATN1

First Posted Date: 2024-02-22

Last Posted Date: 2024-05-10

Lead Sponsor: University College, London

Target Recruit Count: 225

Registration Number: NCT06273150

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
🇬🇧
University College London, London, United Kingdom
🇺🇸
NYU Grossman School of Medicine, New York, New York, United States

Vertical Ridge Augmentation Strategies

Phase 3

Not yet recruiting

Conditions: Alveolar Ridge Trauma
Complication of Surgical Procedure
Alveolar Bone Resorption
Alveolar Bone Loss

Interventions: Procedure: VRA + d-PTFE membrane
Procedure: VRA + RPM
Procedure: VRA + e-PTFE membrane
Procedure: VRA + customised Ti-mesh

First Posted Date: 2024-02-05

Last Posted Date: 2024-02-05

Lead Sponsor: University College, London

Target Recruit Count: 148

Registration Number: NCT06242782

BELIDE: Better Living With Non-memory-led Dementia

Not Applicable

Recruiting

Conditions: Dementia

Interventions: Behavioral: Better Living with Non-memory led Dementia programme
Other: Waiting list

First Posted Date: 2024-02-05

Last Posted Date: 2024-06-21

Lead Sponsor: University College, London

Target Recruit Count: 238

Registration Number: NCT06241287

Locations: 🇬🇧
University College London, London, United Kingdom

Coloured-light in Retinitis Pigmentosa.

Not Applicable

Not yet recruiting

Conditions: Retinitis Pigmentosa

Interventions: Device: Coloured-light torch
Device: Different coloured-light torch

First Posted Date: 2024-01-25

Last Posted Date: 2024-01-25

Lead Sponsor: University College, London

Target Recruit Count: 70

Registration Number: NCT06224114

Locations: 🇬🇧
Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis

Not Applicable

Recruiting

Conditions: Decompensated Cirrhosis

Interventions: Device: CirrhoCare management system

First Posted Date: 2024-01-25

Last Posted Date: 2025-05-06

Lead Sponsor: University College, London

Target Recruit Count: 214

Registration Number: NCT06223893

Locations: 🇬🇧
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
🇬🇧
Royal Sussex County Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, United Kingdom
🇬🇧
Walsgrave General Hospital, University Hospital Coventry & Warwickshire NHS Trust, Coventry, United Kingdom

and more 12 locations

Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students

Not Applicable

Recruiting

Conditions: Anxiety
Internalizing Problems
Depression
Low Mood

Interventions: Behavioral: CBT-informed school-based counselling

First Posted Date: 2024-01-03

Last Posted Date: 2024-01-03

Lead Sponsor: University College, London

Target Recruit Count: 60

Registration Number: NCT06188962

Locations: 🇬🇧
Place2Be services within UK schools, Multiple Cities Across The UK, United Kingdom

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