Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2020-12-19
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 30
- Registration Number
- NCT02388620
- Locations
- 🇺🇸
Anaheim Clinical Trials, Anaheim, California, United States
🇺🇸Orlando Clinical Research Center, Orlando, Florida, United States
🇺🇸University of Miami, Coral Gables, Florida, United States
Multiple Patient Program to Ensure Access to LCZ696 Treatment to Patients Diagnosed With Heart Failure With Reduced Ejection Fraction (HF-rEF)
- Conditions
- Heart Failure With Reduced Ejection Fraction (HF-rEF)
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2021-02-15
- Lead Sponsor
- Novartis Pharmaceuticals
- Registration Number
- NCT02389933
- Locations
- 🇦🇪
Novartis Investigative Site, Ras Al Khaimah, United Arab Emirates
CINC424A2X01B Rollover Protocol
- Conditions
- Primary MyelofibrosisPolycythemia VeraThalassemiaAcute Myeloid LeukemiaGraft Versus Host Disease
- Interventions
- First Posted Date
- 2015-03-12
- Last Posted Date
- 2025-05-30
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 356
- Registration Number
- NCT02386800
- Locations
- 🇹🇷
Novartis Investigative Site, Talas Kayseri, Turkey
A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations
- Conditions
- Advanced Malignancies That Harbor IDHR132 Mutations
- Interventions
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2025-03-25
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 166
- Registration Number
- NCT02381886
- Locations
- 🇺🇸
Uni Of TX MD Anderson Cancer Cntr, Houston, Texas, United States
🇺🇸Dana Farber Cancer Institute SC (1), Boston, Massachusetts, United States
🇺🇸Columbia University Medical Center- New York Presbyterian Onc Dept., New York, New York, United States
RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity
- Conditions
- Retinopathy of Prematurity
- Interventions
- Procedure: Laser therapy
- First Posted Date
- 2015-03-03
- Last Posted Date
- 2018-11-14
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 224
- Registration Number
- NCT02375971
- Locations
- 🇬🇧
Novartis Investigative Site, Portsmouth, United Kingdom
PCA062 in pCAD-positive Tumors.
- Conditions
- Triple Negative Breast CancerHead & Neck CancerEsophageal Cancer
- Interventions
- First Posted Date
- 2015-03-03
- Last Posted Date
- 2020-12-19
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 47
- Registration Number
- NCT02375958
- Locations
- 🇪🇸
Novartis Investigative Site, Madrid, Spain
A Phase 1 Study of Osilodrostat (LCI699) in Healthy Volunteers and Subjects With Impaired Hepatic Function
- First Posted Date
- 2015-02-26
- Last Posted Date
- 2020-12-19
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 33
- Registration Number
- NCT02372084
- Locations
- 🇺🇸
University of Miami / Clinical Research Services, Inc. Boynton Beach, Miami, Florida, United States
🇺🇸Orlando Clinical Research Center, Orlando, Florida, United States
🇺🇸DaVita Clinical Research, Minneapolis, Minnesota, United States
Fingolimod Effect on Cytokine and Chemokine Levels
- Conditions
- Relapsing Remitting Multiple Sclerosis
- Interventions
- First Posted Date
- 2015-02-26
- Last Posted Date
- 2019-09-30
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 126
- Registration Number
- NCT02373098
- Locations
- 🇹🇷
Novartis Investigative Site, Istanbul, Turkey
A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- First Posted Date
- 2015-02-25
- Last Posted Date
- 2019-08-09
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 776
- Registration Number
- NCT02371629
- Locations
- 🇸🇪
Novartis Investigative Site, Lund, Sweden
Study of the Safety of PIM447 in Combination With Ruxolitinib (INC424) and LEE011 in Patients With Myelofibrosis
- First Posted Date
- 2015-02-25
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 15
- Registration Number
- NCT02370706
- Locations
- 🇬🇧
Novartis Investigative Site, London, United Kingdom