Deferasirox BID (Twice a Day) in Transfusion Dependent Thalassemia Patients With Inadequate Response to High Doses
- Conditions
- Focus on Transfusion Dependent Thalassemia Patients Who Are Inadequate Responders to Deferasirox > 35mg/kgQD
- Interventions
- First Posted Date
- 2013-09-24
- Last Posted Date
- 2017-04-20
- Lead Sponsor
- Novartis Pharmaceuticals
- Registration Number
- NCT01948817
Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD
- Conditions
- Age-related Macular DegenerationChoroidal Neovascularization
- Interventions
- First Posted Date
- 2013-09-24
- Last Posted Date
- 2017-04-17
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 650
- Registration Number
- NCT01948830
- Locations
- 🇬🇧
Novartis Investigative Site, Sunderland, United Kingdom
Expanded Treatment Protocol With LDK378 in ALK(+) NSCLC
- Conditions
- Non-small Cell Lung Cancer (NSCLC)
- First Posted Date
- 2013-09-20
- Last Posted Date
- 2020-11-03
- Lead Sponsor
- Novartis Pharmaceuticals
- Registration Number
- NCT01947608
- Locations
- 🇺🇸
Emory University School of Medicine/Winship Cancer Institute, Atlanta, Georgia, United States
🇺🇸Massachusetts General Hospital Mass General, Boston, Massachusetts, United States
🇺🇸Stanford University, Stanford, California, United States
Safety and Efficacy of Fingolimod in MS Patients in China
- Conditions
- Multiple Sclerosis (Relapsing Remitting)
- Interventions
- Drug: Placebo (6mos) + open label fingolimod (6 mos)
- First Posted Date
- 2013-09-12
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- Novartis Pharmaceuticals
- Registration Number
- NCT01941004
Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme
- Conditions
- Recurrent Glioblastoma Multiforme
- Interventions
- First Posted Date
- 2013-09-04
- Last Posted Date
- 2020-12-09
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 35
- Registration Number
- NCT01934361
- Locations
- 🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸MD Anderson Cancer Center/University of Texas, Houston, Texas, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant
- Conditions
- Single Umbilical Cord Blood TransplantationNon-myeloablative ConditioningAcute Lymphocytic LeukemiaMyelodysplastic SyndromeNon-Hodgkin's LymphomaMultiple MyelomaChronic Lymphocytic Leukemia
- Interventions
- First Posted Date
- 2013-08-28
- Last Posted Date
- 2021-01-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 9
- Registration Number
- NCT01930162
- Locations
- 🇺🇸
Novartis Investigative Site, Minneapolis, Minnesota, United States
Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris
- First Posted Date
- 2013-08-28
- Last Posted Date
- 2021-10-08
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 13
- Registration Number
- NCT01930175
- Locations
- 🇨🇳
Novartis Investigative Site, Taipei, Taiwan
Phase 1b Trial of BGJ398/BYL719 in Solid Tumors
- Conditions
- Advanced Solid TumorsMetastatic Solid Tumors
- Interventions
- First Posted Date
- 2013-08-26
- Last Posted Date
- 2020-12-09
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 62
- Registration Number
- NCT01928459
- Locations
- 🇺🇸
H. Lee Moffitt Cancer Center & Research Institute Moffitt 4, Tampa, Florida, United States
🇺🇸University of Michigan Comprehensive Cancer Center SC, Ann Arbor, Michigan, United States
🇺🇸Karmanos Cancer Institute Dept of Onc, Detroit, Michigan, United States
Efficacy and Safety of Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility in sIBM Patients
- Conditions
- Sporadic Inclusion Body Myositis
- Interventions
- Drug: BYM338/bimagrumabDrug: Placebo
- First Posted Date
- 2013-08-19
- Last Posted Date
- 2017-08-11
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 251
- Registration Number
- NCT01925209
- Locations
- 🇬🇧
Novartis Investigative Site, Newcastle upon Tyne, United Kingdom
Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women
- First Posted Date
- 2013-08-15
- Last Posted Date
- 2018-09-14
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 340
- Registration Number
- NCT01923168
- Locations
- 🇺🇸
Emory University School of Medicine/Winship Cancer Institute SC, Atlanta, Georgia, United States
🇺🇸Los Angeles Hematology/Oncology Medical Group Onc Dept., Los Angeles, California, United States
🇺🇸Presbyterian Hospital of Dallas TexasOncology@PresbyterianHosp, Dallas, Texas, United States