MedPath

Commons, Marty

๐Ÿ‡บ๐Ÿ‡ธUnited States
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Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration

Phase 3
Completed
Conditions
Neovascular Age Related Macular Degeneration
Interventions
Drug: RTH258
First Posted Date
2019-04-29
Last Posted Date
2021-01-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
34
Registration Number
NCT03930641
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Novartis Investigative Site, Richmond, Virginia, United States

Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema

Phase 2
Completed
Conditions
Diabetic Macular Edema
Interventions
Drug: LKA651
Drug: Lucentis
First Posted Date
2019-04-25
Last Posted Date
2024-06-20
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
91
Registration Number
NCT03927690
Locations
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Novartis Investigative Site, Kocaeli, Turkey

This Was a Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines

Phase 2
Completed
Conditions
Chronic Spontaneous Urticaria
Interventions
Drug: LOU064 Arm 1
Drug: LOU064 Arm 2
Drug: LOU064 Arm 5
Drug: LOU064 Arm 4
Drug: Placebo arm
Drug: LOU064 Arm 3
Drug: LOU064 Arm 6
First Posted Date
2019-04-24
Last Posted Date
2022-04-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
311
Registration Number
NCT03926611
Locations
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Novartis Investigative Site, Plymouth, United Kingdom

Single Dose and Multiple Dose Study to Assess Safety and Tolerability of LOU064

Phase 1
Completed
Conditions
Healthy Volunteers, Atopic Diathesis and Atopic Dermatitis
Interventions
Drug: LOU064
Drug: Placebo
First Posted Date
2019-04-18
Last Posted Date
2021-10-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
185
Registration Number
NCT03918980
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

Novartis Investigative Site, Leiden, Netherlands

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema

Phase 3
Completed
Conditions
Diabetic Macular Edema
Interventions
First Posted Date
2019-04-17
Last Posted Date
2022-08-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
517
Registration Number
NCT03917472
Locations
๐Ÿ‡ธ๐Ÿ‡ฐ

Novartis Investigative Site, Zvolen, Slovakia

COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure

Phase 3
Completed
Conditions
Heart Failure
Erectile Dysfunction
Heart Failure, Systolic
Interventions
First Posted Date
2019-04-17
Last Posted Date
2024-02-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
27
Registration Number
NCT03917459
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Novartis Investigative Site, Wermsdorf, Germany

An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.

Phase 3
Terminated
Conditions
Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions
First Posted Date
2019-04-10
Last Posted Date
2021-10-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
52
Registration Number
NCT03909295
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

Novartis Investigative Site, Shinagawa-ku, Tokyo, Japan

A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- Antihistamines

Phase 3
Completed
Conditions
Chronic Spontaneous Urticaria
Interventions
Biological: Ligelizumab
First Posted Date
2019-04-09
Last Posted Date
2024-03-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
66
Registration Number
NCT03907878
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

Novartis Investigative Site, Hiroshima, Japan

AScalate: Treat-to-target in Axial Spondyloarthritis

Phase 3
Completed
Conditions
Axial Spondyloarthritis
Interventions
Biological: Secukinumab/Adalimumab-Biosimilar
Other: Standard-of-care
First Posted Date
2019-04-08
Last Posted Date
2023-07-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
305
Registration Number
NCT03906136
Locations
๐Ÿ‡ฉ๐Ÿ‡ช

Novartis Investigative Site, Ulm, Germany

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome

Phase 2
Completed
Conditions
Sjรถgren Syndrome
Interventions
Drug: CFZ533
Other: Placebo
First Posted Date
2019-04-05
Last Posted Date
2023-09-15
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
273
Registration Number
NCT03905525
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Novartis Investigative Site, Manchester, United Kingdom

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