Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration
- Conditions
- Neovascular Age-Related Macular Degeneration
- Interventions
- Drug: RTH258/Brolucizumab
- First Posted Date
- 2020-02-11
- Last Posted Date
- 2024-11-07
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 295
- Registration Number
- NCT04264819
- Locations
- 🇫🇷
Novartis Investigative Site, Vincennes, France
A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab
- Conditions
- In Escalation: All Patients With Solid Tumors and LymphomaIn Expansion: Melanoma, Non-small Cell Lung Cancer
- Interventions
- First Posted Date
- 2020-02-07
- Last Posted Date
- 2025-05-06
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 60
- Registration Number
- NCT04261439
- Locations
- 🇺🇸
City of Hope National Medical, Duarte, California, United States
🇺🇸Moores UCSD Cancer Center, La Jolla, California, United States
🇨🇳Novartis Investigative Site, Taipei, Taiwan
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss
- Conditions
- Triple Negative Breast Neoplasms
- Interventions
- First Posted Date
- 2020-02-05
- Last Posted Date
- 2025-05-23
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 137
- Registration Number
- NCT04251533
- Locations
- 🇺🇸
University of California LA, Los Angeles, California, United States
🇺🇸Hematology and Oncology Clinic, Baton Rouge, Louisiana, United States
🇺🇸Mayo Clinic Rochester, Rochester, Minnesota, United States
Safety and Preliminary Efficacy of JBH492 Monotherapy in Patients With CLL and NHL
- Conditions
- Chronic Lymphocytic LeukemiaNon-Hodgkins Lymphoma
- Interventions
- First Posted Date
- 2020-01-27
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 25
- Registration Number
- NCT04240704
- Locations
- 🇪🇸
Novartis Investigative Site, Barcelona, Catalunya, Spain
A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration
- Conditions
- Neovascular Age Related Macular Degeneration
- Interventions
- Drug: RTH258/Brolucizumab
- First Posted Date
- 2020-01-23
- Last Posted Date
- 2024-10-09
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 210
- Registration Number
- NCT04239027
- Locations
- 🇫🇷
Novartis Investigative Site, Toulouse Cedex 9, France
KAZ954 Alone and With PDR001, NZV930 and NIR178 in Advanced Solid Tumors
- Conditions
- Solid Tumors
- Interventions
- First Posted Date
- 2020-01-23
- Last Posted Date
- 2025-05-18
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 77
- Registration Number
- NCT04237649
- Locations
- 🇺🇸
University Of California LA, Los Angeles, California, United States
🇺🇸Northwestern University Med School, Chicago, Illinois, United States
🇺🇸Uni of TX MD Anderson Cancer Cntr, Houston, Texas, United States
A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD)
- Conditions
- Plaque PsoriasisNon-alcoholic Fatty Liver Disease
- Interventions
- Biological: Control Arm - placeboBiological: Investigational Arm - secukinumab
- First Posted Date
- 2020-01-23
- Last Posted Date
- 2024-02-29
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 10
- Registration Number
- NCT04237116
- Locations
- 🇪🇸
Novartis Investigative Site, Valencia, Comunidad Valenciana, Spain
Study of Safety, Tolerability and Clinical Outcomes of Egaten in Fascioliasis Patients (6 Years of Age or Older).
- First Posted Date
- 2020-01-18
- Last Posted Date
- 2025-06-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 300
- Registration Number
- NCT04230148
- Locations
- 🇻🇳
Novartis Investigative Site, Quy Nhon, Binh Dinh, Vietnam
Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL)
- Conditions
- Acute Lymphoblastic Leukemia
- Interventions
- Biological: Tisagenlecleucel
- First Posted Date
- 2020-01-13
- Last Posted Date
- 2023-01-30
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 5
- Registration Number
- NCT04225676
- Locations
- 🇺🇸
Childrens Hospital Los Angeles Divisionof Hematology/Oncology, Los Angeles, California, United States
🇺🇸Ann and Robert H Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸UT Southwestern Medical Center, Dallas, Texas, United States
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab
- First Posted Date
- 2019-12-26
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 1033
- Registration Number
- NCT04210843
- Locations
- 🇻🇳
Novartis Investigative Site, Ho Chi Minh, Vietnam