MedPath

Commons, Marty

🇺🇸United States
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Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH).

Phase 2
Completed
Conditions
Hemorrhagic Stroke
Intracerebral Hemorrhage (ICH)
Interventions
Drug: BAF312 solution
Drug: Matching Placebo for BAF312 solution
Drug: Matching Placebo for BAF312 tablet
Drug: BAF312 tablet
First Posted Date
2017-11-09
Last Posted Date
2022-08-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT03338998
Locations
🇺🇸

Novartis Investigative Site, Charlottesville, Virginia, United States

Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

Phase 1
Terminated
Conditions
Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)
Interventions
Drug: Placebo Cutaneous Cream application
Drug: Cutaneous Cream application
First Posted Date
2017-11-07
Last Posted Date
2020-12-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
40
Registration Number
NCT03333694
Locations
🇧🇪

Novartis Investigative Site, Liege, Belgium

Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.

Phase 2
Completed
Conditions
Malaria
Interventions
Drug: KAE609
Drug: Coartem
First Posted Date
2017-11-07
Last Posted Date
2021-10-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
188
Registration Number
NCT03334747
Locations
🇺🇬

Novartis Investigative Site, Tororo, Uganda

Study on Safety, Tolerability and Prelimenary Efficacy of LNA043 in Patients Undergoing Autologous Chondrocyte Implantation

Phase 2
Terminated
Conditions
Knee Cartilage Lesion
Interventions
Biological: LNA043
Biological: placebo to LNA043
First Posted Date
2017-11-07
Last Posted Date
2021-10-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
14
Registration Number
NCT03334812
Locations
🇦🇹

Novartis Investigative Site, Wien, Austria

Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC

Phase 1
Active, not recruiting
Conditions
EGFR-mutant Non-small Cell Lung Cancer
Interventions
Drug: EGF816
Drug: LXH254
Drug: trametinib
Drug: ribociclib
Drug: gefitinib
Drug: INC280
First Posted Date
2017-11-06
Last Posted Date
2024-07-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
105
Registration Number
NCT03333343
Locations
🇨🇳

Novartis Investigative Site, Taipei, Taiwan

Study of Efficacy and Safety of AMG 334 in Adult Episodic Migraine Patients

Phase 3
Completed
Conditions
Episodic Migraine
Interventions
Biological: Erenumab
Other: Placebo
First Posted Date
2017-11-06
Last Posted Date
2021-10-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
900
Registration Number
NCT03333109
Locations
🇻🇳

Novartis Investigative Site, Hanoi, Vietnam

Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous Urticaria

Phase 3
Completed
Conditions
Chronic Spontaneous Urticaria
Interventions
Drug: Omalizumab
Drug: Placebo
First Posted Date
2017-11-01
Last Posted Date
2020-11-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
418
Registration Number
NCT03328897
Locations
🇨🇳

Novartis Investigative Site, Shanghai, China

A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity

Phase 2
Completed
Conditions
Obesity
Interventions
Drug: LIK066
Drug: Placebo
First Posted Date
2017-10-25
Last Posted Date
2024-06-26
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
126
Registration Number
NCT03320941
Locations
🇯🇵

Novartis Investigative Site, Toshima-ku, Tokyo, Japan

A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitor

Phase 2
Completed
Conditions
Advanced Breast Cancer
Interventions
First Posted Date
2017-10-18
Last Posted Date
2024-01-23
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
159
Registration Number
NCT03312738
Locations
🇨🇳

Novartis Investigative Site, Wuhan, China

Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

Phase 1
Terminated
Conditions
Solid Tumors
Interventions
Drug: LHC165
Biological: PDR001
First Posted Date
2017-10-04
Last Posted Date
2024-06-20
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
45
Registration Number
NCT03301896
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

UCLA, Los Angeles, California, United States

🇪🇸

Novartis Investigative Site, Madrid, Spain

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