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Commons, Marty

🇺🇸United States
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Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function.

Phase 2
Completed
Conditions
Renal Impairment
Interventions
First Posted Date
2017-04-27
Last Posted Date
2021-01-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
53
Registration Number
NCT03131479
Locations
🇺🇸

Novartis Investigative Site, Orlando, Florida, United States

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

Phase 2
Terminated
Conditions
Alzheimers Disease
Interventions
Drug: CNP520 50mg
Drug: CNP520 15mg
Other: Matching placebo
First Posted Date
2017-04-27
Last Posted Date
2021-08-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
1145
Registration Number
NCT03131453
Locations
🇺🇸

Meridien Research, 2300 Maitland center, Pkwy Ste 230, Maitland, Florida, United States

🇺🇸

Syrentis Clinical Research, 1401 N Tustin Ave, Suite 130, Santa Ana, California, United States

🇬🇧

Novartis Investigative Site, London, United Kingdom

and more 33 locations

Phase III B in Acute Lymphoblastic Leukemia

Phase 3
Completed
Conditions
Acute Lymphoblastic Leukemia
Interventions
Biological: CTL019
First Posted Date
2017-04-21
Last Posted Date
2021-07-21
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
69
Registration Number
NCT03123939
Locations
🇪🇸

Novartis Investigative Site, Esplugues de Llobregat, Barcelona, Spain

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Phase 1
Active, not recruiting
Conditions
Advanced EGFR Mutant Non Small Cell LungCancer (NSCLC)
KRAS G12-mutant NSCLC
Esophageal Squamous Cell Cancer (SCC)
Head/Neck SCC
Melanoma
Advanced Gastrointestinal Stromal Tumors (GIST)
Advanced NRAS/BRAFT wt Cutaneous Melanoma
Interventions
Drug: TNO155 in combination with EGF816 (nazartinib)
First Posted Date
2017-04-14
Last Posted Date
2025-05-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
227
Registration Number
NCT03114319
Locations
🇺🇸

H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

🇺🇸

Dana Farber Cancer Center, Boston, Massachusetts, United States

🇺🇸

Memorial Sloane Ketterin Cancer Ctr, New York, New York, United States

and more 2 locations

An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML)

Conditions
FLT3-mutated Acute Myeloid Leukemia
First Posted Date
2017-04-14
Last Posted Date
2019-10-15
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT03114228
Locations
🇨🇦

Novartis Investigative Site, Montreal, Quebec, Canada

Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2017-04-13
Last Posted Date
2022-02-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
26
Registration Number
NCT03111992
Locations
🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇺🇸

Sarah Cannon Research Institute, Nashville, Tennessee, United States

🇪🇸

Novartis Investigative Site, Madrid, Spain

Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma

Phase 2
Completed
Conditions
Asthma
First Posted Date
2017-04-11
Last Posted Date
2021-01-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
38
Registration Number
NCT03108027
Locations
🇬🇧

Novartis Investigative Site, Machester, United Kingdom

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Phase 3
Completed
Conditions
Chronic Myelogenous Leukemia
Interventions
First Posted Date
2017-04-10
Last Posted Date
2025-04-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
233
Registration Number
NCT03106779
Locations
🇺🇸

Dana Farber Cancer Center, Boston, Massachusetts, United States

🇺🇸

University of Michigan Clinical Trials Office, Ann Arbor, Michigan, United States

🇺🇸

Utah Huntsman Cancer Center, Salt Lake City, Utah, United States

and more 8 locations

A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults

Phase 2
Completed
Conditions
Obesity
Overweight
Interventions
Drug: Placebo
First Posted Date
2017-04-04
Last Posted Date
2020-02-06
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
460
Registration Number
NCT03100058
Locations
🇬🇧

Novartis Investigative Site, Stevenage, United Kingdom

A Long-term Safety Study of QMF149 in Japanese Participants With Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
First Posted Date
2017-04-04
Last Posted Date
2020-02-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
51
Registration Number
NCT03100500
Locations
🇯🇵

Novartis Investigative Site, Toshima-ku, Tokyo, Japan

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