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Pulmocide Ltd.

Pulmocide Ltd. logo
🇬🇧United Kingdom
Ownership
Holding
Established
2013-01-01
Employees
11
Market Cap
-
Website
http://www.pulmocide.com

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

Phase 3
Recruiting
Conditions
Refractory IPA
Interventions
Drug: Placebo
First Posted Date
2022-02-14
Last Posted Date
2025-04-18
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
123
Registration Number
NCT05238116
Locations
🇫🇷

Clinical Research Site 097, Paris, France

🇫🇷

Clinical Research Site 059, Strasbourg, France

🇩🇪

Clinical Research Site 071, Würzburg, Bavaria, Germany

and more 95 locations

A Safety Study of PC945 (Opelconazole) Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients (OPERA-S Study)

Phase 2
Completed
Conditions
Pulmonary Aspergillosis
Interventions
Drug: Standard of Care
First Posted Date
2021-09-08
Last Posted Date
2024-10-08
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
102
Registration Number
NCT05037851
Locations
🇺🇸

Clinical Research Site 2, Houston, Texas, United States

🇺🇸

Clinical Research Site 3, Houston, Texas, United States

🇺🇸

Research Site, Saint Louis, Missouri, United States

and more 2 locations

The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients.

Phase 2
Terminated
Conditions
Lung Transplant Infection
Aspergillosis
Interventions
Drug: Standard of Care
First Posted Date
2019-04-05
Last Posted Date
2021-07-16
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
2
Registration Number
NCT03905447
Locations
🇬🇧

Papworth Hospital, Papworth Everard, Cambridge, United Kingdom

🇬🇧

Wythenshawe Hospital, Manchester, United Kingdom

🇬🇧

Harefield Hospital, Harefield, Uxbridge, United Kingdom

The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis

Phase 2
Terminated
Conditions
Cystic Fibrosis
Aspergillosis
Interventions
First Posted Date
2019-03-12
Last Posted Date
2021-07-16
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
4
Registration Number
NCT03870841
Locations
🇬🇧

Northwest Lung Research Centre, Manchester, United Kingdom

🇬🇧

Royal Brompton Hospital, London, United Kingdom

The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases

Phase 2
Terminated
Conditions
Asthma
Respiratory Aspergillosis
COPD
Bronchiectasis
Respiratory Candidiasis
Interventions
Drug: Placebo
First Posted Date
2018-11-19
Last Posted Date
2020-06-12
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
13
Registration Number
NCT03745196
Locations
🇬🇧

Glenfield Hospital, Leicester, United Kingdom

🇬🇧

Northwest Lung Research Centre, Manchester, United Kingdom

🇬🇧

Royal Brompton Hospital, London, United Kingdom

and more 1 locations

Anti-viral Effect of PC786 on RSV Infection on HSCT Recipients

Phase 2
Terminated
Conditions
Respiratory Syncytial Virus Infections
Interventions
Drug: Placebo
Drug: SOC
First Posted Date
2018-10-22
Last Posted Date
2019-06-12
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
5
Registration Number
NCT03715023
Locations
🇬🇧

Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom

🇬🇧

Birmingham Heartlands Hospital, Birmingham, United Kingdom

🇬🇧

Bristol Haematology and Oncology Centre, Bristol, United Kingdom

and more 4 locations

A Study of PC786 to Evaluate the Antiviral Activity, Safety and Pharmacokinetics of Multiple Doses in an RSV Challenge Study

Phase 1
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Drug: Placebo/vehicle
First Posted Date
2017-12-22
Last Posted Date
2018-05-16
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
56
Registration Number
NCT03382431
Locations
🇬🇧

hVIVO Services Ltd, London, United Kingdom

A Study to Investigate the Safety and Tolerability of Single and Repeat Doses of PC786

Phase 1
Completed
Conditions
Respiratory Syncytial Virus (RSV)
Interventions
Drug: PC786 - Repeat doses
Drug: PC786 - Single doses
Drug: Placebo - Repeat doses
Drug: Placebo - Single doses
First Posted Date
2017-08-01
Last Posted Date
2017-12-21
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
39
Registration Number
NCT03236233
Locations
🇬🇧

Hammersmith Medicines Research, London, United Kingdom

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945

Phase 1
Completed
Conditions
Aspergillosis
Interventions
Drug: PC945 - repeat doses
Drug: PC945 - single doses
Drug: Placebo - single doses
Drug: Placebo - repeat doses
First Posted Date
2016-03-22
Last Posted Date
2018-05-01
Lead Sponsor
Pulmocide Ltd
Target Recruit Count
29
Registration Number
NCT02715570
Locations
🇬🇧

Parexel EPCU, Harrow, Middlesex, United Kingdom

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