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The Case Comprehensive Cancer Center

The Case Comprehensive Cancer Center logo
🇺🇸United States
Ownership
Subsidiary
Established
1826-01-01
Employees
5K
Market Cap
-
Website
http://www.case.edu/cancer

Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation

Early Phase 1
Recruiting
Conditions
Allogeneic Hematopoietic Cell Transplantation
Interventions
First Posted Date
2020-04-02
Last Posted Date
2025-04-16
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
20
Registration Number
NCT04332341
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma

Phase 2
Terminated
Conditions
Urothelial Carcinoma
Interventions
First Posted Date
2020-03-26
Last Posted Date
2025-02-25
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
4
Registration Number
NCT04322643
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N

Phase 1
Active, not recruiting
Conditions
Basal Cell Carcinoma of the Head and Neck
Interventions
Other: Tissue collection
First Posted Date
2020-03-26
Last Posted Date
2025-05-15
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
13
Registration Number
NCT04323202
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas

Early Phase 1
Withdrawn
Conditions
Malignant Melanoma
Interventions
Other: RNA-sequencing
Other: Gene expression profiling
First Posted Date
2020-02-26
Last Posted Date
2020-07-27
Lead Sponsor
Case Comprehensive Cancer Center
Registration Number
NCT04285749

Effects of Early Palliative Care Integration on Patients With Newly Diagnosed Multiple Myeloma

Not Applicable
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
Other: Palliative Care
Other: FACT-MM questionnaire
Other: HADS questionnaire
First Posted Date
2020-01-30
Last Posted Date
2025-04-02
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
20
Registration Number
NCT04248244
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity

Active, not recruiting
Conditions
DCIS
Invasive Breast Cancer
Interventions
Other: Stool sample
Other: Skin Swab Sample
First Posted Date
2020-01-28
Last Posted Date
2024-06-18
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
23
Registration Number
NCT04245150
Locations
🇺🇸

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Phase 2
Recruiting
Conditions
Spine Stereotactic Radiosurgery (sSRS)
Spine Metastases
Interventions
Device: Diagnostic MRI
Device: Planning MRI
Other: Simulation CT
Other: QOL assessment
Other: Brief pain inventory (BPI)
Radiation: sSRS in 1 fraction
Radiation: sSRS in 2 fraction
First Posted Date
2020-01-06
Last Posted Date
2025-01-06
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
130
Registration Number
NCT04218617
Locations
🇺🇸

Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Vitamin B12 for Aromatase Inhibitors Associated Musculoskeletal Symptoms in Breast Cancer

Not Applicable
Withdrawn
Conditions
HR-positive Breast Cancer
Interventions
Other: Blood collection
Dietary Supplement: Vitamin B12
Other: Brief Pain Inventory - Short Form survey
Other: FACT-ES Trial Outcome Index (Version 4)
Other: Questionnaire to Assess Adherence to Aromatase Inhibitors
Other: Demographics Questionnaire
First Posted Date
2019-12-19
Last Posted Date
2024-08-21
Lead Sponsor
Case Comprehensive Cancer Center
Registration Number
NCT04205786
Locations
🇺🇸

Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Pembrolizumab With Axitinib in Recurrent Endometrial Cancer

Phase 2
Withdrawn
Conditions
Recurrent Endometrial Cancer
Interventions
First Posted Date
2019-12-13
Last Posted Date
2020-11-05
Lead Sponsor
Case Comprehensive Cancer Center
Registration Number
NCT04197219

Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT

Not Applicable
Active, not recruiting
Conditions
Myeloma
Stem Cell Transplant Complications
Lymphoma
Allogeneic and Autologous Stem Cell Transplant
Interventions
Other: physical therapy consult
Other: Cognitive Assessment
Other: Cancer Aging Research Group (CARG) assessment
Other: Medication Review
Other: Nutrition assessment
Other: Laboratory studies
Other: Patient satisfaction questionnaire
Other: Physician Questionnaire
Other: Patient follow-up questionnaire
First Posted Date
2019-12-11
Last Posted Date
2025-04-22
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
20
Registration Number
NCT04194840
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

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