DeepMed Research

The Case Comprehensive Cancer Center

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary

Established: 1826-01-01

Employees: 5K

Market Cap: -

Website: http://www.case.edu/cancer

Clinical Trials

Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer

Phase 2

Completed

Conditions: Acinar Cell Adenocarcinoma of the Pancreas
Recurrent Pancreatic Cancer
Stage IV Pancreatic Cancer
Duct Cell Adenocarcinoma of the Pancreas

Interventions: Drug: metformin hydrochloride
Drug: oxaliplatin
Drug: leucovorin calcium
Drug: fluorouracil
Other: laboratory biomarker analysis

First Posted Date: 2012-08-16

Last Posted Date: 2021-08-10

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 50

Registration Number: NCT01666730

Locations: 🇺🇸
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
🇺🇸
Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

High-Dose Stereotactic Radiation for Prostate Cancer

Not Applicable

Completed

Conditions: Stage I Prostate Cancer
Stage IIB Prostate Cancer
Adenocarcinoma of the Prostate
Recurrent Prostate Cancer
Stage IIA Prostate Cancer
Stage III Prostate Cancer

Interventions: Radiation: stereotactic body radiation therapy
Procedure: quality-of-life assessment
Other: laboratory biomarker analysis

First Posted Date: 2012-08-14

Last Posted Date: 2020-05-21

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 35

Registration Number: NCT01664130

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Phase 1

Completed

Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma
Intraocular Lymphoma
Nodal Marginal Zone B-cell Lymphoma
Peripheral T-cell Lymphoma
Recurrent Adult Burkitt Lymphoma
Recurrent Adult Diffuse Large Cell Lymphoma
Recurrent Adult Diffuse Mixed Cell Lymphoma
Recurrent Adult Diffuse Small Cleaved Cell Lymphoma
Recurrent Adult Grade III Lymphomatoid Granulomatosis
Recurrent Adult Hodgkin Lymphoma

Interventions: Drug: fludarabine phosphate
Drug: methoxyamine
Other: laboratory biomarker analysis
Other: pharmacological study
Genetic: western blotting
Other: mass spectrometry
Genetic: DNA analysis

First Posted Date: 2012-08-07

Last Posted Date: 2015-08-13

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 20

Registration Number: NCT01658319

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer

Phase 1

Completed

Conditions: Leydig Cell Tumor
Ovarian Sarcoma
Ovarian Stromal Cancer
Pseudomyxoma Peritonei
Recurrent Cervical Cancer
Recurrent Endometrial Carcinoma
Recurrent Fallopian Tube Cancer
Recurrent Ovarian Epithelial Cancer
Recurrent Ovarian Germ Cell Tumor
Recurrent Primary Peritoneal Cavity Cancer

Interventions: Radiation: stereotactic body radiation therapy
Drug: carboplatin
Drug: gemcitabine hydrochloride
Other: laboratory biomarker analysis
Other: pharmacogenomic studies

First Posted Date: 2012-07-30

Last Posted Date: 2015-08-04

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 12

Registration Number: NCT01652794

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors

Not Applicable

Terminated

Conditions: Malignant Brain Tumors

Interventions: Other: Research Questionnaires
Other: Palliative Care Team
Other: Educational Information Session for Patients and Caregivers
Other: Contact every 2 weeks
Other: Follow-up Surgical Visit Session
Other: Medical and/or Radiation Oncology Appointment Session

First Posted Date: 2012-07-30

Last Posted Date: 2013-08-29

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 1

Registration Number: NCT01652768

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Screening and Risk Factors of Colon Neoplasia

Completed

Conditions: Colon Cancer

Interventions: Other: Stool DNA Test
Procedure: biopsies of rectal and colon mucosa
Other: Questionnaires

First Posted Date: 2012-07-24

Last Posted Date: 2021-02-09

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 3315

Registration Number: NCT01647776

Locations: 🇺🇸
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Prospective Chart-Review: Impact of Combination - Digital Breast Tomosynthesis + Digital Mammography

Withdrawn

Conditions: Breast Cancer

First Posted Date: 2012-05-08

Last Posted Date: 2016-02-17

Lead Sponsor: Case Comprehensive Cancer Center

Registration Number: NCT01593384

Positron Emission Tomography/Magnetic Resonance Imaging in Patients

Not Applicable

Terminated

Conditions: Melanoma
Malignant Neoplasm
Head and Neck Cancer
Lung Cancer
Unspecified Adult Solid Tumor, Protocol Specific
Colon Cancer
Lymphoma
Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Device: magnetic resonance imaging with positron emission tomography scanning

First Posted Date: 2012-03-20

Last Posted Date: 2020-02-24

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 98

Registration Number: NCT01557881

Locations: 🇺🇸
University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy

Phase 2

Completed

Conditions: Recurrent Breast Cancer
Stage I Breast Cancer
Stage IIIC Breast Cancer
Radiation Toxicity
Stage IIIA Breast Cancer
Stage II Breast Cancer
Stage IIIB Breast Cancer
Stage IV Breast Cancer

Interventions: Dietary Supplement: distilled water
Dietary Supplement: alkaline water
Radiation: external beam radiation therapy (EBRT)

First Posted Date: 2011-12-08

Last Posted Date: 2015-06-18

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 45

Registration Number: NCT01487954

Locations: 🇺🇸
University Hospitals-Westlake, Westlake, Ohio, United States

Music Therapy on Nausea and Pain for Autologous Stem Cell

Not Applicable

Completed

Conditions: Multiple Myeloma
Non-Hodgkin Lymphoma
Hodgkin Lymphoma

Interventions: Other: Music Therapy
Other: No music therapy

First Posted Date: 2011-12-07

Last Posted Date: 2013-08-02

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 108

Registration Number: NCT01487031

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

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