The Case Comprehensive Cancer Center

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary

Established: 1826-01-01

Employees: 5K

Market Cap: -

Website: http://www.case.edu/cancer

Clinical Trials

Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma

Phase 2

Terminated

Conditions: Brain Tumor
Anaplastic Astrocytoma
Anaplastic Ependymoma
Anaplastic Oligodendroglioma
Brain Stem Glioma
Giant Cell Glioblastoma
Glioblastoma
Gliosarcoma
Mixed Glioma

Interventions: Drug: ritonavir
Drug: lopinavir

First Posted Date: 2010-03-29

Last Posted Date: 2013-06-10

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 19

Registration Number: NCT01095094

Locations: 🇺🇸
Cleveland Clinic Taussig Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Phase 2

Completed

Conditions: Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)
Childhood Acute Megakaryocytic Leukemia (M7)
Childhood Acute Monocytic Leukemia (M5b)
Childhood Myelodysplastic Syndromes
Recurrent Childhood Large Cell Lymphoma
Recurrent Mantle Cell Lymphoma
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome

Interventions: Procedure: double-unit umbilical cord blood transplantation
Other: cytogenetic analysis
Procedure: bone marrow aspiration
Other: fluorescence in situ hybridization
Drug: busulfan
Drug: cyclophosphamide
Drug: anti-thymocyte globulin
Drug: methylprednisolone
Drug: cyclosporine
Drug: mycophenolate mofetil
Other: flow cytometry
Procedure: allogeneic hematopoietic stem cell transplantation

First Posted Date: 2010-03-26

Last Posted Date: 2019-01-23

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 14

Registration Number: NCT01093586

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Radiosurgery Plus Bevacizumab in Glioblastoma

Early Phase 1

Terminated

Conditions: Gliosarcoma
Brain Tumor
Glioblastoma

Interventions: Radiation: radiosurgery
Biological: bevacizumab
Drug: irinotecan hydrochloride

First Posted Date: 2010-03-15

Last Posted Date: 2018-07-03

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 9

Registration Number: NCT01086345

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Temsirolimus and Bevacizumab in Hormone-Resistant Metastatic Prostate Cancer That Did Not Respond to Chemotherapy

Phase 1

Completed

Conditions: Prostate Cancer

Interventions: Drug: temsirolimus
Biological: bevacizumab
Genetic: polymorphism analysis
Other: laboratory biomarker analysis

First Posted Date: 2010-03-09

Last Posted Date: 2019-08-21

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 22

Registration Number: NCT01083368

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
🇺🇸
CCF-Willoughby Hills, Willoughby Hills, Ohio, United States

Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies

Phase 2

Completed

Conditions: Ovarian Stromal Cancer
Recurrent Cervical Cancer
Stage IV Vulvar Cancer
Stage IVA Vaginal Cancer
Stage IVB Cervical Cancer
Recurrent Ovarian Epithelial Cancer
Recurrent Ovarian Germ Cell Tumor
Recurrent Uterine Sarcoma
Recurrent Vaginal Cancer
Recurrent Vulvar Cancer

Interventions: Radiation: stereotactic radiosurgery
Procedure: quality-of-life assessment

First Posted Date: 2010-03-03

Last Posted Date: 2013-11-28

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 50

Registration Number: NCT01079832

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Phase 1

Terminated

Conditions: Adult Non-Hodgkin Lymphoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma
Noncontiguous Stage II Small Lymphocytic Lymphoma
Recurrent Adult Burkitt Lymphoma
Contiguous Stage II Adult Diffuse Large Cell Lymphoma
Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma
Contiguous Stage II Marginal Zone Lymphoma
Recurrent Adult Diffuse Small Cleaved Cell Lymphoma
Recurrent Adult Grade III Lymphomatoid Granulomatosis

Interventions: Drug: lenalidomide
Biological: rituximab
Genetic: polymerase chain reaction
Genetic: nucleic acid sequencing
Genetic: polymorphism analysis
Other: flow cytometry
Other: laboratory biomarker analysis

First Posted Date: 2010-01-11

Last Posted Date: 2015-11-26

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 5

Registration Number: NCT01045928

Locations: 🇺🇸
Fairview Cancer Hospital, Cleveland, Ohio, United States
🇺🇸
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Study of Tumor Tissue Samples From Patients With Stage I, Stage II, or Stage III Malignant Melanoma

Terminated

Conditions: Melanoma (Skin)

First Posted Date: 2009-10-08

Last Posted Date: 2016-05-17

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 5

Registration Number: NCT00991991

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Quality of Life in Younger Leukemia and Lymphoma Survivors

Completed

Conditions: Anxiety Disorder
Cancer Survivor
Fatigue
Leukemia
Long-term Effects Secondary to Cancer Therapy in Adults
Lymphoma
Lymphoproliferative Disorder
Pain
Psychosocial Effects of Cancer and Its Treatment
Small Intestine Cancer

First Posted Date: 2009-08-11

Last Posted Date: 2011-08-24

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 48

Registration Number: NCT00956475

Locations: 🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye

Completed

Conditions: Intraocular Melanoma

First Posted Date: 2009-08-06

Last Posted Date: 2015-01-30

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 150

Registration Number: NCT00952939

Locations: 🇺🇸
Cleveland Clinic Cole Eye Institute, Cleveland, Ohio, United States

Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases

Early Phase 1

Completed

Conditions: Breast Cancer

Interventions: Biological: bevacizumab
Biological: trastuzumab
Drug: carboplatin
Drug: docetaxel
Other: laboratory biomarker analysis

First Posted Date: 2009-07-30

Last Posted Date: 2020-07-27

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 20

Registration Number: NCT00949247

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
🇺🇸
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
🇺🇸
University Hospitals Monarch, Mayfield Heights, Ohio, United States

and more 2 locations

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