PainReform
- Country
- 🇮🇱Israel
- Ownership
- Public
- Established
- 2007-01-01
- Employees
- 7
- Market Cap
- $1.9M
- Website
- http://www.painreform.com
- Introduction
PainReform Ltd. is a pharmaceutical company, which focuses on reformulation of established therapeutics. It offers PRF-110, an oil-based, viscous, clear solution that is deposited directly into the surgical wound bed prior to closure to provide localized and extended post-operative analgesia. The company was founded by Lihu Avitov and Dan Teleman in 2007 and is headquartered in Herzliya, Israel.
Clinical Trials
4
Trial Phases
3 Phases
Drug Approvals
0
Drug Approvals
No drug approvals found
This company may not have drug approvals in our database
Clinical Trials
Distribution across different clinical trial phases (4 trials with phase data)• Click on a phase to view related trials
A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2023-12-18
- Lead Sponsor
- PainReform LTD
- Target Recruit Count
- 415
- Registration Number
- NCT05773846
- Locations
- 🇺🇸
Woodland International Research Group, Little Rock, Arkansas, United States
🇺🇸Clinical Pharmacology of Miami, Miami, Florida, United States
🇺🇸Midwest Clinical Research Center, Dayton, Ohio, United States
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of PRF110 in Bunionectomy Surgery
- First Posted Date
- 2016-05-27
- Last Posted Date
- 2016-05-27
- Lead Sponsor
- PainReform LTD
- Target Recruit Count
- 15
- Registration Number
- NCT02784327
- Locations
- 🇮🇱
The Chaim Sheba Medical Center, Ramat Gan, Israel
🇮🇱Assaf Harofeh Medical Center, Zerifin, Israel
A Single-dose Open-Label Study to Assess the Safety and Preliminary Efficacy of PRF 110 in Open Herniorrhaphy Surgery
- Conditions
- Post Operative Pain
- Interventions
- Drug: PRF110- oily solution (Ropivacaine)
- First Posted Date
- 2012-09-10
- Last Posted Date
- 2020-11-16
- Lead Sponsor
- PainReform LTD
- Target Recruit Count
- 15
- Registration Number
- NCT01681966
- Locations
- 🇮🇱
Western Galil Medical Center, Nahariya, Israel
🇮🇱Assaf Harofeh Medical Center, Rishon LeZion, Israel
🇮🇱Sourasky Medical Center, Tel Aviv, Israel
A Safety and Effectiveness Pilot Study of PRF-108 and PRF-110 in Healthy Volunteers
- First Posted Date
- 2009-04-17
- Last Posted Date
- 2020-11-16
- Lead Sponsor
- PainReform LTD
- Target Recruit Count
- 15
- Registration Number
- NCT00883194
- Locations
- 🇮🇱
Hadassah University Hospital, Jerusalem, Israel
News
PainReform's PRF-110 Phase 3 Trial Fails to Meet Primary Endpoint in Post-Surgical Pain Management
PainReform's Phase 3 clinical trial of PRF-110 for post-surgical pain management in bunionectomy patients did not meet its primary endpoint.
PainReform's PRF-110 Shows Early Post-Surgical Pain Reduction in Phase 3 Trial
PainReform's PRF-110 demonstrated statistically significant superiority over placebo in reducing pain within the first 48 hours post-bunionectomy, according to initial Phase 3 data.
PainReform's PRF-110 Shows Promise in Phase 3 Bunionectomy Trial, Data Incoherence Hinders Full Analysis
PainReform's PRF-110 demonstrated statistically significant pain reduction compared to placebo in the first 48 hours post-bunionectomy, suggesting effective early postoperative pain relief.
PainReform's PRF-110 Shows Compatibility with Surgical Sutures in Clinical Trials
PainReform's PRF-110, a non-opioid post-surgical pain relief solution, demonstrates compatibility with both non-absorbable and resorbable sutures in human clinical trials.