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Iovance Biotherapeutics

Iovance Biotherapeutics logo
🇺🇸United States
Ownership
Public
Established
2007-01-01
Employees
557
Market Cap
$3.4B
Website
http://www.iovance.com
Introduction

Iovance Biotherapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of cell therapies as novel cancer immunotherapy products. Its lead product candidate, LN-144 for metastatic melanoma, is an autologous adoptive cell therapy utilizing tumor-infiltrating lymphocytes (TIL), which are T cells derived from patients' tumors. The company was founded by Robert T. Brooke on September 17, 2007, and is headquartered in San Carlos, CA.

Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma

Phase 2
Active, not recruiting
Conditions
Cervical Carcinoma
Interventions
First Posted Date
2017-04-11
Last Posted Date
2025-05-07
Lead Sponsor
Iovance Biotherapeutics, Inc.
Target Recruit Count
189
Registration Number
NCT03108495
Locations
🇺🇸

St. Joseph's Hospital and Medical Center Center For Women's Health, Phoenix, Arizona, United States

🇺🇸

University of Southern California, Los Angeles, California, United States

🇺🇸

University of California San Diego, San Diego, California, United States

and more 40 locations

Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & Neck

Phase 2
Completed
Conditions
Squamous Cell Carcinoma of the Head and Neck
Interventions
Biological: LN-145
Biological: LN-145-S1
First Posted Date
2017-03-20
Last Posted Date
2023-10-12
Lead Sponsor
Iovance Biotherapeutics, Inc.
Target Recruit Count
64
Registration Number
NCT03083873
Locations
🇺🇸

University of Alabama, Birmingham, Alabama, United States

🇺🇸

University of California San Diego, La Jolla, California, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

and more 19 locations

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Metastatic Melanoma
Interventions
First Posted Date
2015-02-10
Last Posted Date
2024-11-26
Lead Sponsor
Iovance Biotherapeutics, Inc.
Target Recruit Count
178
Registration Number
NCT02360579
Locations
🇺🇸

University of California San Diego Moores Cancer Center, La Jolla, California, United States

🇺🇸

The Angeles Clinic and Research Institute, Los Angeles, California, United States

🇺🇸

University of California Los Angeles - David Geffen School of Medicine - Westwood Rheumatology, Los Angeles, California, United States

and more 54 locations
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