University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

Safety and Immunogenicity of Candidate HIV Vaccines Given Sequentially

Phase 1

Completed

Conditions: Healthy

Interventions: Biological: ChAdOx1.HTI and MVA.HTI

First Posted Date: 2020-09-24

Last Posted Date: 2022-09-01

Lead Sponsor: University of Oxford

Target Recruit Count: 10

Registration Number: NCT04563377

Locations: 🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

Enhanced Detection in Glioma Excision

Not Applicable

Terminated

Conditions: Glioma

Interventions: Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using ultra-high sensitivity camera
Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using in-built operative microscope camera
Diagnostic Test: Biopsies

First Posted Date: 2020-09-21

Last Posted Date: 2024-03-22

Lead Sponsor: University of Oxford

Target Recruit Count: 4

Registration Number: NCT04556929

Locations: 🇬🇧
John Radcliffe Hospital, Oxford, Oxfordshire, United Kingdom

A Study to Test Three Experimental HIV Vaccines in Healthy Adults.

Phase 1

Conditions: HIV-1-infection

Interventions: Biological: Vaccine
Biological: Placebo

First Posted Date: 2020-09-17

Last Posted Date: 2022-06-22

Lead Sponsor: University of Oxford

Target Recruit Count: 88

Registration Number: NCT04553016

Locations: 🇺🇬
Medical Research and Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine Uganda Research Unit, Masaka, Uganda
🇿🇲
Center for Family Health Research in Zambia, Lusaka, Zambia
🇰🇪
Kenya Medical Research Institute Wellcome Trust Programme, Kilifi, Kenya

and more 1 locations

The Short and Long-term Cardiovascular Consequences of Critical Illness: The C3 Study

Recruiting

Conditions: Critical Illness
Stroke
Atrium; Fibrillation
Atrial Flutter
Myocardial Infarction

Interventions: Other: Admission to ICU

First Posted Date: 2020-09-11

Last Posted Date: 2023-04-20

Lead Sponsor: University of Oxford

Target Recruit Count: 80000

Registration Number: NCT04545437

Locations: 🇬🇧
Oxford University Hospitals, Oxford, Oxfordshire, United Kingdom
🇬🇧
Royal Berkshire NHS Foundation Trust, Reading, Berkshire, United Kingdom
🇬🇧
Imperial College Healthcare NHS Trust, London, United Kingdom

Pancreatic Enzymes and Bile Acids in Acutely Ill Severely Malnourished Children

Phase 2

Active, not recruiting

Conditions: MALNUTRITION, CHILD
SEPSIS

Interventions: Other: Pancreatic Enzyme placebo
Other: Ursodeoxycholic acid placebo
Drug: Pancreatic Enzyme
Drug: Ursodeoxycholic acid

First Posted Date: 2020-09-09

Last Posted Date: 2023-02-24

Lead Sponsor: University of Oxford

Target Recruit Count: 400

Registration Number: NCT04542473

Locations: 🇺🇬
Mulago Hospital, Kampala, Uganda
🇲🇼
Queen Elizabeth Central Hospital, Blantyre, Malawi
🇰🇪
KEMRI WT Clinical Trials Facility, Kilifi, Kenya

and more 1 locations

A Study of a Candidate COVID-19 Vaccine (COV003)

Phase 3

Conditions: Coronavirus

Interventions: Biological: MenACWY prime & saline placebo boost + paracetamol
Biological: ChAdOx1 nCoV-19 single dose + paracetamol
Biological: MenACWY single dose + paracetamol
Biological: ChAdOx1 nCoV-19 two dose + paracetamol

First Posted Date: 2020-09-02

Last Posted Date: 2020-11-27

Lead Sponsor: University of Oxford

Target Recruit Count: 10300

Registration Number: NCT04536051

Locations: 🇧🇷
Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande Do Sul, Brazil
🇧🇷
CRIE, Universidade Federal de São Paulo, São Paulo, Brazil
🇧🇷
Centro de Pesquisas Clinicas de Natal (CPCLIN), Natal, Rio Grande Do Norte, Brazil

and more 2 locations

Star Homes Project 2

Not Applicable

Recruiting

Conditions: Respiratory Tract Infection Acute
Diarrhoea;Acute
Malaria

Interventions: Other: Star Homes
Other: Traditional African houses

First Posted Date: 2020-08-27

Last Posted Date: 2024-03-19

Lead Sponsor: University of Oxford

Target Recruit Count: 2750

Registration Number: NCT04529434

Locations: 🇹🇿
CSK Research Solutions, Dar Es Salaam, Mtwara, Tanzania

Capturing MultiORgan Effects of COVID-19

Conditions: Multi-Organ Disorder
Coronavirus Infection

Interventions: Diagnostic Test: Magnetic Resonance Imaging

First Posted Date: 2020-08-12

Last Posted Date: 2020-08-18

Lead Sponsor: University of Oxford

Target Recruit Count: 616

Registration Number: NCT04510025

Locations: 🇬🇧
University of Oxford, Oxford, United Kingdom

Characterizing Humoral Immune Response to Mosquito Bites

Not Applicable

Recruiting

Conditions: Malaria
Dengue

Interventions: Biological: Mosquito bites

First Posted Date: 2020-07-20

Last Posted Date: 2024-04-03

Lead Sponsor: University of Oxford

Target Recruit Count: 147

Registration Number: NCT04478370

Locations: 🇹🇭
Shoklo Malaria Research unit (SMRU), Mae Sot, Tak, Thailand

Incidences, Causes, and Outcomes of Febrile Illness in Rural South and Southeast Asia

Recruiting

Conditions: Febrile Illness

First Posted Date: 2020-07-20

Last Posted Date: 2024-05-09

Lead Sponsor: University of Oxford

Target Recruit Count: 100000

Registration Number: NCT04478578

Locations: 🇧🇩
Building Resources Across Communities (BRAC), Dhaka, Bangladesh
🇰🇭
Action for Health Development (AHEAD), Battambang, Cambodia
🇱🇦
Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Vientiane, Vientiane Prefecture, Lao People's Democratic Republic

and more 4 locations

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