MedPath

BCG vaccine

Generic Name
BCG vaccine
Drug Type
Biotech
Unique Ingredient Identifier
8VJE55B0VG
Background

BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

Associated Conditions
Non-Invasive Bladder Urothelial Carcinoma, Recurrent Superficial Bladder Cancer, Tuberculosis (TB), Urothelial Carcinoma Recurrent, Carcinoma in situ of urinary bladder

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Phase 2
Recruiting
Conditions
Urinary Bladder Neoplasms
Non-Muscle Invasive Bladder Neoplasms
Carcinoma in Situ
Interventions
First Posted Date
2025-02-18
Last Posted Date
2025-05-09
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
308
Registration Number
NCT06833073
Locations
🇺🇸

University of Missouri Health Care ( Site 0126), Columbia, Missouri, United States

🇺🇸

NHO Revive Research Institute, LLC ( Site 0137), Lincoln, Nebraska, United States

🇺🇸

OHSU Knight Cancer Institute - South Waterfront ( Site 0110), Portland, Oregon, United States

and more 8 locations

Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder Cancer

Phase 2
Not yet recruiting
Conditions
Non-muscle Invasive Bladder Cancer (NMIBC)
Interventions
Drug: N-803 and Gemcitabine
First Posted Date
2025-02-17
Last Posted Date
2025-02-17
Lead Sponsor
ImmunityBio, Inc.
Target Recruit Count
20
Registration Number
NCT06829823

BCG for Therapeutic Use Phase Ⅲ Clinical Trial

First Posted Date
2024-12-24
Last Posted Date
2025-05-18
Lead Sponsor
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Target Recruit Count
438
Registration Number
NCT06747455
Locations
🇨🇳

The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China

🇨🇳

The First Affiliated Hospital of USTC, Hefei, Anhui, China

🇨🇳

Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, Beijing, China

and more 33 locations

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

Phase 1
Recruiting
Conditions
Non-Muscle Invasive Bladder Carcinoma
Stage 0is Bladder Cancer AJCC v8
Stage 0a Bladder Cancer AJCC v8
Stage I Bladder Cancer AJCC v8
Interventions
Procedure: Cystoscopy
Other: Home Health Encounter
Other: Questionnaire Administration
First Posted Date
2024-11-26
Last Posted Date
2025-04-27
Lead Sponsor
Mayo Clinic
Target Recruit Count
40
Registration Number
NCT06704191
Locations
🇺🇸

Mayo Clinic in Florida, Jacksonville, Florida, United States

ID93/GLA-SE Vaccination + BCG Challenge

Not Applicable
Recruiting
Conditions
Tuberculosis
Interventions
Biological: ID93/GLA-SE
First Posted Date
2024-11-01
Last Posted Date
2025-04-10
Lead Sponsor
University of Oxford
Target Recruit Count
48
Registration Number
NCT06670755
Locations
🇬🇧

Centre for Clinical Vaccinology and Tropical Medicine, Oxford, Oxfordshire, United Kingdom

Trained Immunity in Fungal Infection and Its Mechanism

First Posted Date
2024-10-07
Last Posted Date
2024-10-07
Lead Sponsor
Zhongnan Hospital
Target Recruit Count
79
Registration Number
NCT06628544
Locations
🇨🇳

Wuhan University, Wuhan, Hubei, China, China

Clinical Study to Investigate the Safety and Tolerance of Therapeutic BCG in Postoperative Adjuvant Therapy in Subjects With Moderate to High-risk Non-muscular Invasive Bladder Cancer (NMIBC)

Phase 1
Completed
Conditions
Non-muscular Invasive Bladder Cancer
Interventions
First Posted Date
2024-04-05
Last Posted Date
2024-04-05
Lead Sponsor
Chengdu CoenBiotech Co., Ltd
Target Recruit Count
10
Registration Number
NCT06350838
Locations
🇨🇳

Hunan Cancer Hospital, Changsha, Hunan, China

Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

Not Applicable
Not yet recruiting
Conditions
Bladder Cancer
Interventions
Procedure: Transurethral resection of bladder tumor
Procedure: Transurethral cryoablation
First Posted Date
2024-03-21
Last Posted Date
2024-03-21
Lead Sponsor
Huashan Hospital
Target Recruit Count
190
Registration Number
NCT06324058

Live Vaccines and Innate Immune Training in COPD.

Phase 4
Recruiting
Conditions
COPD
Trained Innate Immunity
Interventions
First Posted Date
2024-02-13
Last Posted Date
2024-05-24
Lead Sponsor
Josefin Eklöf
Target Recruit Count
60
Registration Number
NCT06257212
Locations
🇩🇰

Department of Internal Medicine, Section of Respiratory Medicine, Hellerup, Copenhagen, Denmark

Clinical Trial for Evaluating the Efficacy and Safety of BCG for Therapeutic Use in the Prevention of Postoperative Recurrence of Medium/High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

Phase 3
Recruiting
Conditions
Non-Muscle Invasive Bladder Cancer
Interventions
First Posted Date
2024-02-05
Last Posted Date
2024-02-05
Lead Sponsor
Chengdu CoenBiotech Co., Ltd
Target Recruit Count
412
Registration Number
NCT06241755
Locations
🇨🇳

Sun Yat-sen Memorial Hospital,Sun Yat-sen University, Guangzhou, Guangdong, China

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