BCG vaccine
- Generic Name
- BCG vaccine
- Drug Type
- Biotech
- Unique Ingredient Identifier
- 8VJE55B0VG
- Background
BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
- Associated Conditions
- Non-Invasive Bladder Urothelial Carcinoma, Recurrent Superficial Bladder Cancer, Tuberculosis (TB), Urothelial Carcinoma Recurrent, Carcinoma in situ of urinary bladder
Safety and Efficacy of BCG Combined With Tislelizumab for BCG-untreated Patients With High-risk Non-muscle Invasive Bladder Cancer
- Conditions
- Non-muscle-invasive Bladder Cancer
- Interventions
- First Posted Date
- 2022-10-14
- Last Posted Date
- 2022-10-14
- Lead Sponsor
- Ruijin Hospital
- Target Recruit Count
- 42
- Registration Number
- NCT05580354
- Locations
- 🇨🇳
Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China
Long Term Effects of BCG Vaccination on Infectious and Immune Mediated Diseases
- Conditions
- InflammationInfectionsBCG Vaccination ReactionCOVID-19
- Interventions
- Biological: Placebo vaccine
- First Posted Date
- 2022-05-24
- Last Posted Date
- 2025-04-20
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 4292
- Registration Number
- NCT05387655
- Locations
- 🇳🇱
Radboud university medical center, Nijmegen, Gelderland, Netherlands
Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa
- First Posted Date
- 2021-07-23
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- Biofabri, S.L
- Target Recruit Count
- 7120
- Registration Number
- NCT04975178
- Locations
- 🇿🇦
South African Tuberculosis Initiative, Brewelskloof Hospital, Worcester, Western Cape, South Africa
Prevention of Acute Respiratory Infection in Taiwanese Institutionalized Elderly
- First Posted Date
- 2021-06-24
- Last Posted Date
- 2022-07-06
- Lead Sponsor
- Harvard Medical School (HMS and HSDM)
- Registration Number
- NCT04938323
Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers
- First Posted Date
- 2021-03-02
- Last Posted Date
- 2025-02-06
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 12
- Registration Number
- NCT04777721
- Locations
- 🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine, Oxford, Oxfordshire, United Kingdom
Can BCG Vaccination at First Health-facility Contact Reduce Early Infant Mortality?
- Conditions
- Infant MortalityBCG
- Interventions
- First Posted Date
- 2020-12-08
- Last Posted Date
- 2024-01-22
- Lead Sponsor
- Bandim Health Project
- Target Recruit Count
- 22800
- Registration Number
- NCT04658680
- Locations
- 🇬🇼
Bandim Health Project, Bissau, Guinea-Bissau
BCG Vaccination to Prevent COVID-19
- Conditions
- COVID-19
- Interventions
- Drug: Preservative-free saline
- First Posted Date
- 2020-11-17
- Last Posted Date
- 2021-03-26
- Lead Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Registration Number
- NCT04632537
BCG Against Covid-19 for Prevention and Amelioration of Severity Trial (BAC to the PAST)
- First Posted Date
- 2020-09-01
- Last Posted Date
- 2021-06-28
- Lead Sponsor
- Harvard Medical School (HMS and HSDM)
- Registration Number
- NCT04534803
Propranolol Adjuvant Treatment of Bladder Cancer
- Conditions
- Bladder Cancer
- Interventions
- First Posted Date
- 2020-07-30
- Last Posted Date
- 2020-07-30
- Lead Sponsor
- Central South University
- Target Recruit Count
- 242
- Registration Number
- NCT04493489
Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants
- Conditions
- Mycobacterium Tuberculosis Infection
- Interventions
- First Posted Date
- 2020-04-17
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- Serum Institute of India Pvt. Ltd.
- Target Recruit Count
- 6940
- Registration Number
- NCT04351685
- Locations
- 🇺🇬
Medical Research Council / Uganda Virus Research Institute and London School of Hygiene and Tropical Medicines (MRC/UVRI and LSHTM) Uganda Research Unit, Entebbe, Uganda
🇺🇬Makerere University/CISMAC, Kampala, Uganda
🇬🇦Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
Drug Development Updates
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