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Kodiak Sciences

🇺🇸United States
Ownership
-
Employees
111
Market Cap
$138.9M
Website
Introduction

Kodiak Sciences, Inc. is a clinical-stage biopharmaceutical company, which engages in the research, development, and commercialization of therapeutics for retinal diseases. Its product pipeline includes KSI-301 for wet AMD, KSI-301 for diabetic eye disease, KSI-501 for DME and uveitis, KSI-201 for resistant wet AMD, and KSI-401 for dry AMD. The company was founded by Stephen A. Charles and Victor Perlroth in 2009 and is headquartered in Palo Alto, CA.

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

Phase 3
Not yet recruiting
Conditions
Macular Edema Secondary to Inflammation
Interventions
Other: Sham Comparator
First Posted Date
2025-05-30
Last Posted Date
2025-05-30
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
150
Registration Number
NCT06996080

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

Phase 3
Not yet recruiting
Conditions
Macular Edema Secondary to Inflammation
Interventions
Other: Sham Comparator
First Posted Date
2025-05-25
Last Posted Date
2025-05-25
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
150
Registration Number
NCT06990399

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK

Phase 3
Recruiting
Conditions
Wet Age-related Macular Degeneration
Interventions
First Posted Date
2024-08-16
Last Posted Date
2025-06-11
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
675
Registration Number
NCT06556368
Locations
🇺🇸

Associated Retina Consultants, Phoenix, Arizona, United States

🇺🇸

Retina Macula Institute of Arizona, Scottsdale, Arizona, United States

🇺🇸

Retina Associates SW, Tucson, Arizona, United States

and more 59 locations

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)

Phase 3
Active, not recruiting
Conditions
Diabetic Retinopathy
Interventions
Other: Sham injection
First Posted Date
2024-02-21
Last Posted Date
2025-03-30
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
255
Registration Number
NCT06270836
Locations
🇺🇸

Retina Associates SW, Tucson, Arizona, United States

🇺🇸

Global Research Management, Inc. - Lugene Eye Institute, Glendale, California, United States

🇺🇸

Retina Consultants of Orange County, Fullerton, California, United States

and more 34 locations

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)

Phase 3
Terminated
Conditions
Non-proliferative Diabetic Retinopathy
Interventions
Other: Sham injection
First Posted Date
2021-10-04
Last Posted Date
2024-04-11
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
253
Registration Number
NCT05066230
Locations
🇺🇸

Charleston Neurosciences Institute, Beaufort, South Carolina, United States

🇺🇸

Retina Specialists of Idaho, Boise, Idaho, United States

🇪🇸

Hospital Universitario Miguel Servet, Zaragoza, Spain

and more 58 locations

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)

Phase 3
Completed
Conditions
Wet Age-related Macular Degeneration
Interventions
Other: Sham Procedure
First Posted Date
2021-07-15
Last Posted Date
2024-07-03
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
557
Registration Number
NCT04964089
Locations
🇺🇸

Ophthalmic Consultants of Boston, Boston, Massachusetts, United States

🇺🇸

Retina Consultants of Texas, Houston, Texas, United States

🇺🇸

Medical Center Ophthalmology Associates, San Antonio, Texas, United States

and more 63 locations

A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)

Phase 3
Terminated
Conditions
Diabetic Macular Edema
Interventions
Other: Sham Procedure
First Posted Date
2020-11-02
Last Posted Date
2024-08-22
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
460
Registration Number
NCT04611152
Locations
🇺🇸

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States

🇺🇸

MidAtlantic Retina, Philadelphia, Pennsylvania, United States

🇺🇸

Ophthalmic Consultants of Boston, Boston, Massachusetts, United States

and more 72 locations

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)

Phase 3
Terminated
Conditions
Diabetic Macular Edema
Interventions
Other: Sham Procedure
First Posted Date
2020-10-27
Last Posted Date
2024-08-22
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
459
Registration Number
NCT04603937
Locations
🇺🇸

Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, Ohio, United States

🇫🇷

CHRU Dijon Complexe Du Bocage, Dijon, Côte-d'Or, France

🇺🇸

Retina Specialists of Idaho, Boise, Idaho, United States

and more 68 locations

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)

Phase 3
Completed
Conditions
Macular Edema
Retinal Vein Occlusion
Interventions
Other: Sham Procedure
First Posted Date
2020-10-19
Last Posted Date
2024-06-26
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
568
Registration Number
NCT04592419
Locations
🇺🇸

Ophthalmic Consultants of Boston, Boston, Massachusetts, United States

🇺🇸

Vitreo Retinal Consultants and Surgeons, Wichita, Kansas, United States

🇺🇸

Tennessee Retina PC, Nashville, Tennessee, United States

and more 137 locations

A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.

Phase 2
Terminated
Conditions
Wet Macular Degeneration
Interventions
Other: Sham Procedure
First Posted Date
2019-08-08
Last Posted Date
2024-07-18
Lead Sponsor
Kodiak Sciences Inc
Target Recruit Count
559
Registration Number
NCT04049266
Locations
🇺🇸

Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, Ohio, United States

🇺🇸

Medical Center Ophthalmology Associates, San Antonio, Texas, United States

🇺🇸

Vitreoretinal Surgery PA, Edina, Minnesota, United States

and more 70 locations
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