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Biogen

Biogen logo
🇺🇸United States
Ownership
Private
Established
1978-01-01
Employees
7.5K
Market Cap
$29.6B
Website
https://www.biogen.com
Introduction

Biogen, Inc. is a biopharmaceutical company, which engages in discovering, developing, and delivering therapies for neurological and neurodegenerative diseases. Its products include TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI and FAMPYRA for the treatment of MS, SPINRAZA for the treatment of SMA, ADUHELM for the treatment of Alzheimer's disease, and FUMADERM for the treatment of severe plaque psoriasis. The company was founded by Charles Weissmann, Heinz Schaller, Kenneth Murray, Walter Gilbert, and Phillip Allen Sharp in 1978 and is headquartered in Cambridge, MA.

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

Phase 1
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Drug: Placebo
First Posted Date
2018-08-10
Last Posted Date
2022-01-14
Lead Sponsor
Biogen
Target Recruit Count
106
Registration Number
NCT03626012
Locations
🇬🇧

Research Site, London, United Kingdom

An Efficacy and Safety Study of BG00011 in Participants With Idiopathic Pulmonary Fibrosis

Phase 2
Terminated
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
Drug: Placebo
First Posted Date
2018-06-29
Last Posted Date
2020-12-11
Lead Sponsor
Biogen
Target Recruit Count
109
Registration Number
NCT03573505
Locations
🇬🇧

Research Site, Leeds, West Yorkshire, United Kingdom

🇺🇸

Reserach Site, Houston, Texas, United States

A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111

Phase 2
Completed
Conditions
Choroideremia
Interventions
First Posted Date
2018-04-25
Last Posted Date
2024-02-23
Lead Sponsor
Biogen
Target Recruit Count
66
Registration Number
NCT03507686
Locations
🇩🇪

Research Site, Tübingen, Germany

Efficacy and Safety of BIIB111 for the Treatment of Choroideremia

Phase 3
Completed
Conditions
Choroideremia
Interventions
Genetic: BIIB111
First Posted Date
2018-04-12
Last Posted Date
2023-12-07
Lead Sponsor
Biogen
Target Recruit Count
169
Registration Number
NCT03496012
Locations
🇬🇧

Research Site, Oxford, United Kingdom

Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2018-03-05
Last Posted Date
2019-05-16
Lead Sponsor
Biogen
Target Recruit Count
80
Registration Number
NCT03454126
Locations
🇬🇧

Hammersmith Medicines Research, London, United Kingdom

🇬🇧

Research Site, Leeds, United Kingdom

Tysabri Observational Cohort Study - Multiple Sclerosis (MS) Registries

Completed
Conditions
Progressive Multifocal Leukoencephalopathy
Interventions
Biological: Tysabri
First Posted Date
2018-01-17
Last Posted Date
2024-03-19
Lead Sponsor
Biogen
Target Recruit Count
80327
Registration Number
NCT03399981
Locations
🇺🇸

Research Site, Cambridge, Massachusetts, United States

Study to Evaluate the Effect of UGT Inhibition by Valproic Acid on the Pharmacokinetics of BIIB074

Phase 1
Completed
Conditions
Drug Interaction
Interventions
First Posted Date
2017-12-28
Last Posted Date
2018-04-20
Lead Sponsor
Biogen
Target Recruit Count
30
Registration Number
NCT03385525
Locations
🇺🇸

Research Site, Dallas, Texas, United States

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease

Phase 2
Terminated
Conditions
Alzheimer's Disease
Interventions
Drug: Placebo
First Posted Date
2017-11-24
Last Posted Date
2022-11-08
Lead Sponsor
Biogen
Target Recruit Count
654
Registration Number
NCT03352557
Locations
🇺🇸

The Research Center of Southern California, Carlsbad, California, United States

🇸🇪

Karolinska Universitetssjukhuset, Huddinge, Stockholm, Sweden

🇮🇹

Ospedale San Raffaele, Milano, Italy

and more 92 locations

A Post-Authorization Safety Study of Interferon Beta Therapy in Participants With Multiple Sclerosis

Completed
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Drug: SC interferon beta-1a
Drug: SC interferon beta-1b
Drug: SC Peginterferon beta-1a
First Posted Date
2017-11-20
Last Posted Date
2019-09-25
Lead Sponsor
Biogen
Target Recruit Count
626
Registration Number
NCT03347370
Locations
🇩🇪

Research Site, Göttingen, Germany

Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy

Phase 2
Terminated
Conditions
Small Fiber Neuropathy
Diabetes Mellitus
Interventions
Drug: Placebo
First Posted Date
2017-11-13
Last Posted Date
2021-05-05
Lead Sponsor
Biogen
Target Recruit Count
265
Registration Number
NCT03339336
Locations
🇫🇷

CHU Nice - Hôpital de l'Archet 1, Nice, France

🇨🇿

Nemocnice Pardubickeho kraje a.s. Pardubicka nemocnice, Pardubice, Czechia

🇩🇪

Diabetologische Schwerpunktpraxis Harburg, Hamburg, Germany

and more 50 locations
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