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Biogen

Biogen logo
🇺🇸United States
Ownership
Private
Established
1978-01-01
Employees
7.5K
Market Cap
$29.6B
Website
https://www.biogen.com
Introduction

Biogen, Inc. is a biopharmaceutical company, which engages in discovering, developing, and delivering therapies for neurological and neurodegenerative diseases. Its products include TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI and FAMPYRA for the treatment of MS, SPINRAZA for the treatment of SMA, ADUHELM for the treatment of Alzheimer's disease, and FUMADERM for the treatment of severe plaque psoriasis. The company was founded by Charles Weissmann, Heinz Schaller, Kenneth Murray, Walter Gilbert, and Phillip Allen Sharp in 1978 and is headquartered in Cambridge, MA.

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

Phase 1
Completed
Conditions
Hearing Loss, Sensorineural
Interventions
Drug: Placebo
First Posted Date
2012-01-26
Last Posted Date
2019-11-21
Lead Sponsor
Biogen
Target Recruit Count
44
Registration Number
NCT01518920
Locations
🇺🇸

Pfizer Investigational Site, Dallas, Texas, United States

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Repeated Doses of PF-04958242 in Healthy Volunteers

Phase 1
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
First Posted Date
2012-01-18
Last Posted Date
2019-11-21
Lead Sponsor
Biogen
Target Recruit Count
39
Registration Number
NCT01511510
Locations
🇺🇸

Pfizer Investigational Site, New Haven, Connecticut, United States

Demonstrate the Bioequivalence of Interferon Beta-1a (INFB) Manufactured by Two Different Processes in Healthy Volunteers

Phase 1
Completed
Conditions
Multiple Sclerosis
Interventions
Drug: Interferon beta-1a (current approved manufacturing process invloving FBS)
Drug: Interferon beta-1a (new process, manufactured without FBS)
First Posted Date
2011-12-28
Last Posted Date
2012-11-19
Lead Sponsor
Biogen
Target Recruit Count
110
Registration Number
NCT01500408
Locations
🇺🇸

Research Site, St. Paul, Minnesota, United States

A Pharmacodynamic Study of Measured Glomerular Filtration Rate in Patients With Chronic Kidney Disease and Type 2 Diabetes

Phase 1
Terminated
Conditions
Chronic Kidney Disease
Type 2 Diabetes
Interventions
Drug: 20 mg bardoxolone methyl
Drug: Placebo
First Posted Date
2011-12-28
Last Posted Date
2023-10-27
Lead Sponsor
Biogen
Target Recruit Count
18
Registration Number
NCT01500798

BIIB023 Proof-of-Concept Study in Participants With Lupus Nephritis

Phase 2
Terminated
Conditions
Lupus Nephritis
Interventions
Biological: BIIB023
Biological: Placebo
Drug: oral corticosteroids
First Posted Date
2011-12-26
Last Posted Date
2017-01-18
Lead Sponsor
Biogen
Target Recruit Count
276
Registration Number
NCT01499355
Locations
🇹🇭

Research Site, Patumwan, Bangkok, Thailand

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)

Phase 1
Completed
Conditions
Spinal Muscular Atrophy
Interventions
First Posted Date
2011-12-19
Last Posted Date
2021-02-18
Lead Sponsor
Biogen
Target Recruit Count
28
Registration Number
NCT01494701
Locations
🇺🇸

Children's Hospital Boston, Boston, Massachusetts, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

🇺🇸

UT Southwestern Medical Center - Children's Medical Center Dallas, Dallas, Texas, United States

and more 1 locations

Canadian Avonex PEN Productivity Study

Completed
Conditions
Multiple Sclerosis
First Posted Date
2011-12-12
Last Posted Date
2015-02-20
Lead Sponsor
Biogen
Target Recruit Count
111
Registration Number
NCT01489748
Locations
🇨🇦

Central Contact, Burlington, Ontario, Canada

Observational Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JC Virus Antibody Negative Participants

Completed
Conditions
Relapsing-Remitting Multiple Sclerosis
First Posted Date
2011-12-05
Last Posted Date
2019-02-12
Lead Sponsor
Biogen
Target Recruit Count
231
Registration Number
NCT01485003
Locations
🇺🇸

Research Site, Tacoma, Washington, United States

An Observational Study to Collect Information on Safety and to Document the Drug Utilization of Fampyra (BIIB041) When Used In Routine Medical Practice

Completed
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2011-11-28
Last Posted Date
2019-06-05
Lead Sponsor
Biogen
Target Recruit Count
4734
Registration Number
NCT01480063
Locations
🇪🇸

Site Research, Bilbao, Vizcaya, Spain

🇪🇸

Research site, San Cristobal de La laguna, Tenerife, Spain

🇨🇦

Reasearch Center, London, Ontario, Canada

and more 2 locations

Open-Label Study to Assess the Effect of Long-Term Prolonged-Release Fampridine (BIIB041) on Quality of Life as Reported by Participants With Multiple Sclerosis

Phase 4
Completed
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2011-11-28
Last Posted Date
2017-03-21
Lead Sponsor
Biogen
Target Recruit Count
901
Registration Number
NCT01480076
Locations
🇬🇧

Research Site, London, United Kingdom

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