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Biogen

Biogen logo
🇺🇸United States
Ownership
Private
Established
1978-01-01
Employees
7.5K
Market Cap
$29.6B
Website
https://www.biogen.com
Introduction

Biogen, Inc. is a biopharmaceutical company, which engages in discovering, developing, and delivering therapies for neurological and neurodegenerative diseases. Its products include TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI and FAMPYRA for the treatment of MS, SPINRAZA for the treatment of SMA, ADUHELM for the treatment of Alzheimer's disease, and FUMADERM for the treatment of severe plaque psoriasis. The company was founded by Charles Weissmann, Heinz Schaller, Kenneth Murray, Walter Gilbert, and Phillip Allen Sharp in 1978 and is headquartered in Cambridge, MA.

Efficacy and Safety Study of BG00012 With Methotrexate in Patients With Active Rheumatoid Arthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: placebo
First Posted Date
2008-12-18
Last Posted Date
2013-09-16
Lead Sponsor
Biogen
Target Recruit Count
153
Registration Number
NCT00810836
Locations
🇸🇰

Research Site, Piestany, Slovakia

Evaluation of Safety and Efficacy of Fludarabine, Cyclophosphamide, and Rituximab (FCR) +/- Lumiliximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia (CLL)

Phase 2
Terminated
Conditions
Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2008-12-03
Last Posted Date
2015-10-02
Lead Sponsor
Biogen
Target Recruit Count
40
Registration Number
NCT00801060
Locations
🇺🇸

University of Florida/Pulmonary, Critical Care & Sleep Medicine, Gainesville, Florida, United States

🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

🇬🇧

Research Site, Bath, Avon, United Kingdom

and more 3 locations

Study of Tysabri (Natalizumab) in Patients Who Failed Anti-TNF-α Therapy

Phase 4
Withdrawn
Conditions
Crohn's Disease
First Posted Date
2008-12-03
Last Posted Date
2016-06-16
Lead Sponsor
Biogen
Registration Number
NCT00801125

Immunogenicity and Safety of Subcutaneously-administered Avonex (Interferon Beta-1a) in Multiple Sclerosis (MS) Patients

Phase 3
Terminated
Conditions
Multiple Sclerosis
Interventions
Drug: BG9418 (interferon beta 1-a)
First Posted Date
2008-11-04
Last Posted Date
2014-05-07
Lead Sponsor
Biogen
Target Recruit Count
3
Registration Number
NCT00784836
Locations
🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

🇺🇸

MS Center at Texas Neurology, Dallas, Texas, United States

BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
Other: Placebo (sterile normal saline)
First Posted Date
2008-10-13
Last Posted Date
2013-09-16
Lead Sponsor
Biogen
Target Recruit Count
53
Registration Number
NCT00771329
Locations
🇺🇸

Research Site, Oklahoma City, Oklahoma, United States

🇷🇺

Research Centre, Yaroslavl, Russian Federation

A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a

Phase 4
Withdrawn
Conditions
Relapsing-remitting Multiple Sclerosis
Interventions
First Posted Date
2008-10-10
Last Posted Date
2024-06-03
Lead Sponsor
Biogen
Registration Number
NCT00771043

Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)

Phase 1
Terminated
Conditions
Progressive Multifocal Leukoencephalopathy
Interventions
First Posted Date
2008-09-04
Last Posted Date
2014-07-31
Lead Sponsor
Biogen
Target Recruit Count
37
Registration Number
NCT00746941
Locations
🇪🇸

Research Site, Madrid, Spain

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency

Phase 2
Terminated
Conditions
Renal Insufficiency
Heart Failure
Interventions
Drug: Placebo
First Posted Date
2008-09-03
Last Posted Date
2023-09-11
Lead Sponsor
Biogen
Target Recruit Count
34
Registration Number
NCT00745316

A Pharmacokinetic (PK) Study of Natalizumab (Tysabri) at Steady State

Phase 4
Completed
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2008-09-01
Last Posted Date
2015-02-10
Lead Sponsor
Biogen
Target Recruit Count
20
Registration Number
NCT00744679
Locations
🇺🇸

Research Site, Latham, New York, United States

Administration of BIIB028 to Subjects With Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors
First Posted Date
2008-07-31
Last Posted Date
2017-01-09
Lead Sponsor
Biogen
Target Recruit Count
43
Registration Number
NCT00725933
Locations
🇺🇸

Research Site, Houston, Texas, United States

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