ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study
- Conditions
- Age Related Macular Degeneration (AMD)
- Interventions
- Genetic: GT005
- First Posted Date
- 2022-08-01
- Last Posted Date
- 2024-03-22
- Lead Sponsor
- Gyroscope Therapeutics Limited
- Target Recruit Count
- 225
- Registration Number
- NCT05481827
- Locations
- ๐บ๐ธ
Retina Consultants San Diego - Poway, Poway, California, United States
๐บ๐ธVitreo Retinal Associates Pa - the Millennium Center Location, Gainesville, Florida, United States
๐บ๐ธSouthwest Retina Research Center, Durango, Colorado, United States
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
- Conditions
- Dry Age-related Macular Degeneration
- First Posted Date
- 2020-09-28
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Gyroscope Therapeutics Limited
- Target Recruit Count
- 255
- Registration Number
- NCT04566445
- Locations
- ๐บ๐ธ
Retina Consultants of Houston, The Woodlands, Texas, United States
๐บ๐ธCleveland Clinic, Cleveland, Ohio, United States
๐บ๐ธRetina Vitreous Associates Medical Group, Beverly Hills, California, United States
EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
- Conditions
- Dry Age-related Macular Degeneration
- Interventions
- Drug: GT005; High DoseDrug: GT005; Low Dose
- First Posted Date
- 2020-06-18
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Gyroscope Therapeutics Limited
- Target Recruit Count
- 98
- Registration Number
- NCT04437368
- Locations
- ๐บ๐ธ
Mid Atlantic Retina, Philadelphia, Pennsylvania, United States
๐บ๐ธMidwest Eye Institute Northside, Indianapolis, Indiana, United States
๐บ๐ธDepartment of Ophthalmology UW Medicine, Seattle, Washington, United States
GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)
- Conditions
- Retinal DiseaseGeographic AtrophyDry Age-related Macular DegenerationMacular DegenerationMacular AtrophyRetinal Degeneration
- First Posted Date
- 2019-03-28
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Gyroscope Therapeutics Limited
- Target Recruit Count
- 83
- Registration Number
- NCT03894020
- Locations
- ๐บ๐ธ
Retina Consultants of Houston, The Woodlands, Texas, United States
๐บ๐ธOphthalamic Consultants of Boston (OCB), Boston, Massachusetts, United States
๐บ๐ธMidwest Eye Institute Northside, Indianapolis, Indiana, United States
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
- Conditions
- Macular DegenerationRetinal DegenerationDry Age-related Macular DegenerationEye DiseasesMacular AtrophyRetinal DiseaseGeographic Atrophy
- Interventions
- Biological: GT005
- First Posted Date
- 2019-02-19
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Gyroscope Therapeutics Limited
- Target Recruit Count
- 56
- Registration Number
- NCT03846193
- Locations
- ๐บ๐ธ
Midwest Eye Institute, Indianapolis, Indiana, United States
๐บ๐ธOphthalamic Consultants of Boston (OCB), Boston, Massachusetts, United States
๐บ๐ธWolfe Eye Clinic, West Des Moines, Iowa, United States