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XBiotech

XBiotech logo
🇺🇸United States
Ownership
Public
Established
2005-01-01
Employees
82
Market Cap
$198M
Website
http://www.xbiotech.com
Introduction

XBiotech, Inc. is a biopharmaceutical company, which engages in the development and commercialization of therapeutic antibodies. Its product pipeline includes oncology, infectious diseases, dermatology and inflammatory disorders. The company was founded by John Simard on March 22, 2005 and is headquartered in Austin, TX.

Clinical Trials

8

Active:1
Completed:3

Trial Phases

2 Phases

Phase 1:4
Phase 2:4

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (50.0%)
Phase 2
4 (50.0%)

Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment

Phase 2
Not yet recruiting
Conditions
Rheumatoid Arthritis
Interventions
Biological: Natrunix 400 mg
Drug: Placebo
First Posted Date
2024-09-19
Last Posted Date
2025-04-22
Lead Sponsor
XBiotech, Inc.
Target Recruit Count
108
Registration Number
NCT06590090

Natrunix in HLA-B27 Positive Subjects With Axial Spondyloarthritis

Phase 2
Not yet recruiting
Conditions
Axial Spondyloarthritis
Interventions
Drug: Placebo
First Posted Date
2024-07-29
Last Posted Date
2024-07-31
Lead Sponsor
XBiotech, Inc.
Target Recruit Count
60
Registration Number
NCT06526377

Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
First Posted Date
2022-05-06
Last Posted Date
2025-01-16
Lead Sponsor
XBiotech, Inc.
Target Recruit Count
243
Registration Number
NCT05363891
Locations
🇺🇸

Medvin Clinical Research, Tujunga, California, United States

🇺🇸

T. Joseph Raoof MD, INC, Encino, California, United States

🇺🇸

Desert Medical Advances, Rancho Mirage, California, United States

and more 19 locations

Natrunix Versus Methotrexate in Rheumatoid Arthritis

Phase 2
Conditions
Rheumatoid Arthritis
Interventions
Drug: Natrunix placebo with MTX (+folate)
Drug: Natrunix with MTX placebo (+folate)
First Posted Date
2022-05-06
Last Posted Date
2022-05-06
Lead Sponsor
XBiotech, Inc.
Target Recruit Count
150
Registration Number
NCT05363917

Natrunix Safety PK Study in Healthy Volunteers

Phase 1
Conditions
Pharmacokinetics
First Posted Date
2021-10-29
Last Posted Date
2022-02-24
Lead Sponsor
XBiotech, Inc.
Target Recruit Count
24
Registration Number
NCT05099510
Locations
🇺🇸

BioBehavioral Research of Austin, A Telemed2U Company, Austin, Texas, United States

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News

XBiotech Halts Rheumatology Program Following Phase II Trial Irregularities with Natrunix

XBiotech has paused its rheumatology program after a Phase II trial of Natrunix for rheumatoid arthritis failed to meet its primary endpoint.

BioAge Labs Faces Securities Lawsuits Following Azelaprag Trial Discontinuation

• BioAge Labs is under investigation for potential securities law violations after discontinuing its Phase 2 trial of azelaprag due to safety concerns. • Multiple law firms have announced investigations and class action lawsuits on behalf of investors who suffered losses following the trial halt. • The STRIDES Phase 2 trial was terminated after liver transaminitis was observed in participants, leading to a significant drop in BioAge's stock price. • Investors who purchased BioAge securities during the IPO period have until March 10, 2025, to seek lead plaintiff status in the class action.

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