Evaluation of an Anti-TREM-1 Treatment on an ex Vivo Human Intestinal Model
- Conditions
- Inflammatory Bowel Diseases
- Interventions
- Other: Additional biopsies and blood samples
- First Posted Date
- 2024-08-30
- Last Posted Date
- 2025-02-27
- Lead Sponsor
- Inotrem
- Target Recruit Count
- 40
- Registration Number
- NCT06580418
- Locations
- ๐ฎ๐น
IRCCS San Raffaele, Milano, Italy
Efficacy and Safety Study of Nangibotide in Patients With COVID-19 Receiving Ventilatory Support
- First Posted Date
- 2020-06-12
- Last Posted Date
- 2023-05-03
- Lead Sponsor
- Inotrem
- Target Recruit Count
- 220
- Registration Number
- NCT04429334
- Locations
- ๐ง๐ช
Clinique universitaire Saint-Luc, Brussels, Belgium
๐ง๐ชZiekenhuis Oost-Limburg, Genk, Belgium
๐ซ๐ทCHU Angers, Angers, France
Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock
- Conditions
- Shock, Septic
- Interventions
- First Posted Date
- 2019-08-14
- Last Posted Date
- 2023-04-11
- Lead Sponsor
- Inotrem
- Target Recruit Count
- 355
- Registration Number
- NCT04055909
- Locations
- ๐ซ๐ฎ
Tampereen yliopistollinen sairaala, Tampere, Finland
๐ง๐ชUZ Gent, Gent, Belgium
๐ง๐ชCHU Marie Curie, Lodelinsart, Belgium
Safety, Tolerability and Pharmacokinetic Profiles of MOTREM (LR12) in Healthy Male Subjects
- First Posted Date
- 2018-03-13
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- Inotrem
- Target Recruit Count
- 27
- Registration Number
- NCT03463044
- Locations
- ๐ฌ๐ง
Richmond Pharmacology Ltd., Croydon, United Kingdom
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM (Nangibotide) in Patients With Septic Shock
- Conditions
- Shock, Septic
- Interventions
- First Posted Date
- 2017-05-18
- Last Posted Date
- 2024-10-07
- Lead Sponsor
- Inotrem
- Target Recruit Count
- 50
- Registration Number
- NCT03158948
- Locations
- ๐ซ๐ท
Inserm Clinical Investigational Center, CHU Dupuytren (there may be other sites in this country), Limoges Cedex, France
๐ณ๐ฑRadboudumc (there may be other sites in this country), Nijmegen, Netherlands
๐ช๐ธHospital Clรญnico San Carlos, Medicina Intensiva (there may be other sites in this country), Madrid, Spain