MAYO CLINIC

Lutetium Lu 177 dotatate demonstrated antitumor activity in patients with metastatic bronchopulmonary neuroendocrine tumors, achieving partial responses in 17% of patients in a real-world study.

A 9-year-old golden retriever with metastatic oral melanoma achieved complete tumor remission after participating in a clinical trial testing inhaled IL-15 immunotherapy at UC Davis.

A Mayo Clinic phase 3 trial demonstrates that de-escalated adjuvant radiation therapy (DART) significantly reduces severe toxicity rates from 11% to 3% compared to standard treatment in HPV-positive oropharyngeal cancer patients.

A custom-built antisense oligonucleotide drug targeting the CHCHD10 gene mutation has slowed ALS progression by more than half in Dr. Rakesh Parekh, marking the first treatment for this specific genetic variant.

TREOS Bio has initiated OBERTO-202, a potentially registration-enabling Phase II trial evaluating PolyPEPI1018 combined with toripalimab and standard care in 140 patients with microsatellite stable metastatic colorectal cancer.

Arctx Medical received FDA Investigational Device Exemption approval to conduct a pivotal clinical trial of its Cool Catheter Kit in approximately 200 acute pancreatitis patients at up to 25 US hospitals.

Former FDA Commissioner Dr. Stephen Hahn has been appointed CEO of Nucleus RadioPharma, a contract development and manufacturing organization specializing in radiopharmaceuticals for targeted cancer therapy.

Ruxolitinib demonstrates sustained efficacy in polycythemia vera with 74% probability of maintaining primary composite response at 5-year follow-up in the RESPONSE trial.

Payer-specific biosimilar mandates create significant inventory management challenges and operational inefficiencies for academic and infusion centers, requiring substantial resources to coordinate care delivery.

iMDx has enrolled its first patient in the GraftAssureDx clinical trial, an observational study designed to validate a kitted transplant rejection monitoring test for kidney transplant recipients.