VA Office of Research and Development

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Clinical Trials

A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms

Not Applicable

Not yet recruiting

Conditions: Psychosocial Functioning
Stress Disorders, Post-Traumatic
Depressive Disorder, Major

First Posted Date: 2024-11-14

Last Posted Date: 2024-11-15

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 40

Registration Number: NCT06689787

Locations: 🇺🇸
VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California, United States

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Phase 1

Not yet recruiting

Conditions: Relapsed Small Cell Lung Cancer
Recurrent Small Cell Lung Cancer

Interventions: Combination Product: Stenoparib/Temozolomide
Drug: Lurbinectedin

First Posted Date: 2024-11-08

Last Posted Date: 2025-05-04

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 166

Registration Number: NCT06681220

Locations: 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States
🇺🇸
VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California, United States
🇺🇸
Jesse Brown VA Medical Center, Chicago, IL, Chicago, Illinois, United States

and more 8 locations

NAFLD Clinical Care Pathway

Not Applicable

Recruiting

Conditions: NAFLD
MASLD

First Posted Date: 2024-11-04

Last Posted Date: 2024-11-04

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 32

Registration Number: NCT06671886

Locations: 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

Not Applicable

Not yet recruiting

Conditions: Stage IV NSCLC
NSCLC
Immunotherapy
Fasting Mimicking Diet

First Posted Date: 2024-11-04

Last Posted Date: 2025-04-08

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 66

Registration Number: NCT06671613

Locations: 🇺🇸
VA Central California Health Care System, Fresno, CA, Fresno, California, United States
🇺🇸
VA Long Beach Healthcare System, Long Beach, CA, Long Beach, California, United States
🇺🇸
Jesse Brown VA Medical Center, Chicago, IL, Chicago, Illinois, United States

and more 1 locations

Driver Training After Stroke

Not yet recruiting

Conditions: Stroke

First Posted Date: 2024-11-04

Last Posted Date: 2024-11-04

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 100

Registration Number: NCT06672107

Locations: 🇺🇸
VA Northern California Health Care System, Mather, CA, Sacramento, California, United States

Pilot Study of Hospital GamePlan4Care

Not Applicable

Recruiting

Conditions: Caregivers

Interventions: Behavioral: Hospital GamePlan4Care
Other: Health Education

First Posted Date: 2024-10-09

Last Posted Date: 2025-02-10

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 50

Registration Number: NCT06634368

Locations: 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States

Cognitive Control Training for Extinction in PTSD

Not Applicable

Recruiting

Conditions: Post-Traumatic Stress Disorders
Stress Disorders, Traumatic
Post Traumatic Stress Disorder
PTSD
Trauma and Stressor Related Disorders

Interventions: Behavioral: Working Memory Training
Other: Sham Training

First Posted Date: 2024-10-07

Last Posted Date: 2024-10-07

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 120

Registration Number: NCT06629064

Locations: 🇺🇸
VA San Diego Healthcare System, San Diego, CA, San Diego, California, United States

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Not Applicable

Not yet recruiting

Conditions: Overweight/Obesity
Stress

Interventions: Behavioral: Exercise

First Posted Date: 2024-10-04

Last Posted Date: 2024-10-04

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 132

Registration Number: NCT06627569

Locations: 🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado, United States

Randomized Trial of SGLT2i in Heart Transplant Recipients

Phase 4

Not yet recruiting

Conditions: Heart Transplant
Cardiovascular Disease
Kidney Disease

Interventions: Drug: Empagliflozin
Drug: Placebo

First Posted Date: 2024-10-03

Last Posted Date: 2025-04-08

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 200

Registration Number: NCT06625073

Locations: 🇺🇸
VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California, United States
🇺🇸
Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville, Tennessee, United States
🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States

and more 3 locations

HealthyTogether: RCT of a Dyadic Weight Management Intervention

Not Applicable

Not yet recruiting

Conditions: Obesity
Overweight

Interventions: Behavioral: HealthyTogether

First Posted Date: 2024-10-01

Last Posted Date: 2025-05-21

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 320

Registration Number: NCT06619041

Locations: 🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado, United States
🇺🇸
VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington, United States

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