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ALX Oncology

ALX Oncology logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2015-01-01
Employees
72
Market Cap
$131.1M
Website
http://www.alxoncology.com
Introduction

ALX Oncology Holdings, Inc. operates as a clinical stage company, which engages in the research and development of therapies for cancer patients. Its objective is to provide clinical therapies for the treatment of myelodysplastic syndromes, acute myeloid leukemia, and a range of solid tumor indications. The company was founded by Corey Goodman, Jaume Pons, and K. Christopher Garcia in March 2015 and is headquartered in South San Francisco, CA.

Clinical Trials

26

Active:20
Completed:0

Trial Phases

2 Phases

Phase 1:20
Phase 2:5

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (25 trials with phase data)• Click on a phase to view related trials

Phase 1
20 (80.0%)
Phase 2
5 (20.0%)

ASPEN-09: A Study of Evorpacept in Combination With Anti-cancer Therapies in Advanced / Metastatic Malignancies

Phase 1
Recruiting
Conditions
Breast Cancer, Metastatic
Colorectal Cancer
Interventions
First Posted Date
2025-06-06
Last Posted Date
2025-06-06
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
280
Registration Number
NCT07007559
Locations
🇺🇸

Gabrail Cancer Center, Canton, Ohio, United States

A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07)

Phase 1
Active, not recruiting
Conditions
Bladder Cancer
Urothelial Carcinoma
Interventions
Drug: Enfortumab Vedotin
First Posted Date
2022-09-01
Last Posted Date
2025-05-11
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
36
Registration Number
NCT05524545
Locations
🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

🇺🇸

Massachusett's General, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 5 locations

A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

Phase 2
Active, not recruiting
Conditions
Gastric Cancer
Gastroesophageal Junction Adenocarcinoma
Gastric Adenocarcinoma
Interventions
First Posted Date
2021-08-12
Last Posted Date
2025-06-12
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
450
Registration Number
NCT05002127
Locations
🇺🇸

The Oncology Institute of Hope & Innovation, Anaheim, California, United States

🇺🇸

University of California Los Angeles, Los Angeles, California, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

and more 80 locations

A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia
AML, Adult
Interventions
First Posted Date
2021-02-16
Last Posted Date
2024-11-27
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
14
Registration Number
NCT04755244
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

🇺🇸

Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

and more 2 locations

Evorpacept (ALX148) in Combination with Pembrolizumab and Chemotherapy in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)

Phase 2
Active, not recruiting
Conditions
Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Interventions
Drug: Cisplatin/Carboplatin; 5FU
First Posted Date
2020-12-19
Last Posted Date
2025-03-25
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
172
Registration Number
NCT04675333
Locations
🇺🇸

Hoag Hospital, Irvine, California, United States

🇺🇸

University of California San Diego, La Jolla, California, United States

🇺🇸

Cedar Sinai Medical Center, Los Angeles, California, United States

and more 41 locations
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