MedPath

ALX Oncology

ALX Oncology logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2015-01-01
Employees
72
Market Cap
$131.1M
Website
http://www.alxoncology.com
Introduction

ALX Oncology Holdings, Inc. operates as a clinical stage company, which engages in the research and development of therapies for cancer patients. Its objective is to provide clinical therapies for the treatment of myelodysplastic syndromes, acute myeloid leukemia, and a range of solid tumor indications. The company was founded by Corey Goodman, Jaume Pons, and K. Christopher Garcia in March 2015 and is headquartered in South San Francisco, CA.

A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07)

Phase 1
Active, not recruiting
Conditions
Bladder Cancer
Urothelial Carcinoma
Interventions
Drug: Enfortumab Vedotin
First Posted Date
2022-09-01
Last Posted Date
2025-05-11
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
36
Registration Number
NCT05524545
Locations
🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

🇺🇸

Massachusett's General, Boston, Massachusetts, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 5 locations

A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

Phase 2
Recruiting
Conditions
Gastric Cancer
Gastroesophageal Junction Adenocarcinoma
Gastric Adenocarcinoma
Interventions
First Posted Date
2021-08-12
Last Posted Date
2024-07-31
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
450
Registration Number
NCT05002127
Locations
🇺🇸

The Oncology Institute of Hope & Innovation, Anaheim, California, United States

🇺🇸

University of California Los Angeles, Los Angeles, California, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

and more 80 locations

A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia
AML, Adult
Interventions
First Posted Date
2021-02-16
Last Posted Date
2024-11-27
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
14
Registration Number
NCT04755244
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

🇺🇸

Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States

🇺🇸

Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States

and more 2 locations

Evorpacept (ALX148) in Combination with Pembrolizumab and Chemotherapy in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)

Phase 2
Active, not recruiting
Conditions
Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Interventions
Drug: Cisplatin/Carboplatin; 5FU
First Posted Date
2020-12-19
Last Posted Date
2025-03-25
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
172
Registration Number
NCT04675333
Locations
🇺🇸

University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida, United States

🇺🇸

Vanderbilt - Ingram Cancer Center, Nashville, Tennessee, United States

🇺🇸

Oregon Health & Science University/ Knight Cancer Institute, Portland, Oregon, United States

and more 41 locations

Evorpacept (ALX148) in Combination with Pembrolizumab in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)

Phase 2
Active, not recruiting
Conditions
Head and Neck Squamous Cell Carcinoma
Head and Neck Cancer
Interventions
First Posted Date
2020-12-19
Last Posted Date
2025-03-25
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
189
Registration Number
NCT04675294
Locations
🇺🇸

The Ohio State University, Columbus, Ohio, United States

🇺🇸

Rutgers Cancer Institute of New Jersey, Newark, New Jersey, United States

🇧🇪

Cliniques Universitaires Saint-Luc, Brussels, Belgium

and more 49 locations

A Study of Evorpacept (ALX148) With Azacitidine for Higher Risk Myelodysplastic Syndrome (ASPEN-02)

Phase 1
Active, not recruiting
Conditions
Higher Risk Myelodysplastic Syndromes
Interventions
First Posted Date
2020-06-04
Last Posted Date
2025-05-04
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
65
Registration Number
NCT04417517
Locations
🇺🇸

University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

🇺🇸

IU Simon Cancer Center, Indianapolis, Indiana, United States

and more 16 locations

A Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)

Phase 1
Active, not recruiting
Conditions
Metastatic Cancer
NonHodgkin Lymphoma
Advanced Cancer
Solid Tumor
Interventions
First Posted Date
2017-01-06
Last Posted Date
2024-03-22
Lead Sponsor
ALX Oncology Inc.
Target Recruit Count
174
Registration Number
NCT03013218
Locations
🇺🇸

Seattle Cancer Care Alliance, Seattle, Washington, United States

🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

and more 7 locations
© Copyright 2025. All Rights Reserved by MedPath