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Lineage Cell Therapeutics

Lineage Cell Therapeutics logo
🇺🇸United States
Ownership
Public
Established
1990-01-01
Employees
75
Market Cap
$171.3M
Website
http://www.lineagecell.com

Clinical Trials

5

Active:2
Completed:2

Trial Phases

1 Phases

Phase 1:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (3 trials with phase data)• Click on a phase to view related trials

Phase 1
3 (100.0%)

A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury

Phase 1
Recruiting
Conditions
Spinal Cord Injury Cervical
Spinal Cord Injury Thoracic
Spinal Cord Injury, Acute
Spinal Cord Injury
Spinal Cord Injury, Chronic
Interventions
First Posted Date
2025-02-24
Last Posted Date
2025-06-12
Lead Sponsor
Lineage Cell Therapeutics, Inc.
Target Recruit Count
10
Registration Number
NCT06841770
Locations
🇺🇸

University of California, San Diego, La Jolla, California, United States

LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1

Active, not recruiting
Conditions
Spinal Cord Injuries
First Posted Date
2023-08-03
Last Posted Date
2024-08-21
Lead Sponsor
Lineage Cell Therapeutics, Inc.
Target Recruit Count
25
Registration Number
NCT05975424
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

Shepherd Center, Atlanta, Georgia, United States

and more 3 locations

LTFU Study of Subjects Who Received GRNOPC1

Active, not recruiting
Conditions
Spinal Cord Injuries
First Posted Date
2023-06-26
Last Posted Date
2024-08-21
Lead Sponsor
Lineage Cell Therapeutics, Inc.
Target Recruit Count
5
Registration Number
NCT05919563
Locations
🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

Shepherd Center, Atlanta, Georgia, United States

🇺🇸

Northwestern Medical Group, Evanston, Illinois, United States

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

Phase 1
Completed
Conditions
Cervical Spinal Cord Injury
Spinal Cord Trauma
Spine Injury
First Posted Date
2014-11-26
Last Posted Date
2021-07-14
Lead Sponsor
Lineage Cell Therapeutics, Inc.
Target Recruit Count
25
Registration Number
NCT02302157
Locations
🇺🇸

Univ. of California at San Diego, La Jolla, California, United States

🇺🇸

Rancho Los Amigos/USC, Los Angeles, California, United States

🇺🇸

Stanford University/Santa Clara Valley Medical Center, San Jose, California, United States

and more 6 locations

Safety Study of GRNOPC1 in Spinal Cord Injury

Phase 1
Completed
Conditions
Spinal Cord Injury
First Posted Date
2010-10-08
Last Posted Date
2020-06-18
Lead Sponsor
Lineage Cell Therapeutics, Inc.
Target Recruit Count
5
Registration Number
NCT01217008
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Stanford University/Santa Clara Valley Medical Center, Palo Alto/San Jose, California, United States

🇺🇸

Shepherd Center, Atlanta, Georgia, United States

and more 4 locations

News

36-Month Results of OpRegen Cell Therapy for Geographic Atrophy to Be Presented at CTS 2025

Long-term 36-month data from the Phase 1/2a trial of RG6501 (OpRegen) for geographic atrophy secondary to AMD will be presented at Clinical Trials at the Summit in June 2025.

Lineage Cell Therapeutics Launches DOSED Study for Novel Spinal Cord Injury Cell Therapy

Lineage Cell Therapeutics has initiated the DOSED clinical study to evaluate OPC1, a stem cell-derived therapy, using a new delivery system for both subacute and chronic spinal cord injury patients.

Emerging Therapies Offer Hope for Geographic Atrophy Treatment

Several therapies are under evaluation in clinical trials for geographic atrophy (GA) secondary to age-related macular degeneration (AMD), addressing the unmet need for effective treatments.

RG6501 Shows Rapid Improvement in Retinal Structure for Geographic Atrophy Patients

Phase 1/2a trial results for RG6501 (OpRegen) demonstrate significant improvements in outer retinal structure within three months of a single administration in patients with geographic atrophy secondary to AMD.

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