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Tango Therapeutics

Tango Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2017-01-01
Employees
140
Market Cap
$1.2B
Website
http://www.tangotx.com
Introduction

Tango Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in discovering and delivering precision cancer medicines. It also identifies novel targets and develops new drugs directed at tumor suppressor gene loss in defined patient populations with high unmet medical need. The company was founded by Alan Ashworth, William G. Kaelin, Jr., Jose Baselga, and Antoni Ribas in 2017 and is headquartered in Boston, MA.

Clinical Trials

6

Active:1
Completed:0

Trial Phases

1 Phases

Phase 1:5

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (6 trials with phase data)• Click on a phase to view related trials

Phase 1
5 (83.3%)
phase_1_2
1 (16.7%)

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Phase 1
Recruiting
Conditions
PDAC
PDAC - Pancreatic Ductal Adenocarcinoma
Lung Cancer
Pancreatic Cancer Metastatic
Thoracic Cancer
NSCLC
RAS Mutation
MTAP Deletion
Interventions
First Posted Date
2025-04-10
Last Posted Date
2025-07-25
Lead Sponsor
Tango Therapeutics, Inc.
Target Recruit Count
133
Registration Number
NCT06922591
Locations
🇺🇸

Nebraska Cancer Specialists, Omaha, Nebraska, United States

🇺🇸

NYU Langone Health, New York, New York, United States

🇺🇸

NEXT Dallas, Irving, Texas, United States

and more 1 locations

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Phase 1
Recruiting
Conditions
Non Small Cell Lung Cancer
Glioma Glioblastoma Multiforme
Glioma, Malignant
Solid Tumor
Non-Small Cell Adenocarcinoma
Lung Cancer
Brain Tumor
Interventions
First Posted Date
2025-02-05
Last Posted Date
2025-07-28
Lead Sponsor
Tango Therapeutics, Inc.
Target Recruit Count
191
Registration Number
NCT06810544
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

NYU Langone Health, New York, New York, United States

and more 3 locations

Study to Evaluate TNG348 Alone and With a PARP Inhibitor in Patients With BRCA 1/2 Mutant or HRD+ Solid Tumors

Phase 1
Terminated
Conditions
Pancreas Cancer
HRD Positive Advanced Ovarian Cancer
Breast Cancer
Ovarian Cancer
BRCA1 Mutation
Prostate Cancer
BRCA-Mutated Ovarian Carcinoma
BRCA-Associated Breast Carcinoma
Interventions
First Posted Date
2023-10-03
Last Posted Date
2024-08-13
Lead Sponsor
Tango Therapeutics, Inc.
Target Recruit Count
7
Registration Number
NCT06065059
Locations
🇺🇸

HealthONE, Denver, Colorado, United States

🇺🇸

Mid Florida Cancer Centers, Orange City, Florida, United States

🇺🇸

Florida Cancer Specialists, Sarasota, Florida, United States

and more 4 locations

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Phase 1
Recruiting
Conditions
Non Small Cell Lung Cancer
Solid Tumors, Adult
Lung Adenocarcinoma
Lung Cancer
Interventions
First Posted Date
2023-06-02
Last Posted Date
2025-07-23
Lead Sponsor
Tango Therapeutics, Inc.
Target Recruit Count
126
Registration Number
NCT05887492
Locations
🇺🇸

NYU Langone Hematology Oncology Associates-Mineola, Mineola, New York, United States

🇺🇸

UCLA Hematology/Oncology, Santa Monica, California, United States

🇺🇸

SCRI at HealthOne, Denver, Colorado, United States

and more 8 locations

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

Phase 1
Recruiting
Conditions
Locally Advanced Solid Tumor
Interventions
First Posted Date
2023-02-17
Last Posted Date
2025-05-06
Lead Sponsor
Tango Therapeutics, Inc.
Target Recruit Count
225
Registration Number
NCT05732831
Locations
🇫🇷

Institut de Cancerologie de l'Ouest - Hôpital Saint Herblain - PPDS, Saint-Herblain, France

🇺🇸

Stanford University, Palo Alto, California, United States

🇺🇸

Grand Valley Oncology, Grand Junction, Colorado, United States

and more 22 locations
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