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VYNE THERAPEUTICS INC

VYNE THERAPEUTICS INC logo
🇮🇱Israel
Ownership
-
Employees
-
Market Cap
$26.5M
Website

Clinical Trials

32

Active:1
Completed:27

Trial Phases

3 Phases

Phase 1:7
Phase 2:16
Phase 3:9

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (32 trials with phase data)• Click on a phase to view related trials

Phase 2
16 (50.0%)
Phase 3
9 (28.1%)
Phase 1
7 (21.9%)

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.

Phase 2
Active, not recruiting
Conditions
Non-segmental Vitiligo
Interventions
Drug: VYN201 Gel
Drug: Vehicle Gel
First Posted Date
2024-07-10
Last Posted Date
2025-06-04
Lead Sponsor
Vyne Therapeutics Inc.
Target Recruit Count
200
Registration Number
NCT06493578
Locations
🇺🇸

Cahaba Dermatology & Skin Health Center, Birmingham, Alabama, United States

🇺🇸

Saguaro Dermatology, Phoenix, Arizona, United States

🇺🇸

Center for Dermatology and Plastic Surgery/CCT Research, Scottsdale, Arizona, United States

and more 44 locations

Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis

Phase 1
Completed
Conditions
Atopic Dermatitis
Interventions
Other: Vehicle
First Posted Date
2021-06-16
Last Posted Date
2022-08-31
Lead Sponsor
Vyne Therapeutics Inc.
Target Recruit Count
21
Registration Number
NCT04927572
Locations
🇺🇸

Investigator #9, Miami, Florida, United States

🇺🇸

Investigator #14, Miami, Florida, United States

🇺🇸

Investigator #12, Miramar, Florida, United States

and more 4 locations

A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Phase 3
Completed
Conditions
Facial Papulopustular Rosacea
Interventions
First Posted Date
2020-10-29
Last Posted Date
2021-01-07
Lead Sponsor
Vyne Therapeutics Inc.
Target Recruit Count
771
Registration Number
NCT04608500
Locations
🇺🇸

Foamix Investigational Site # 207, Glendale, Arizona, United States

🇺🇸

Foamix Investigational Site # 202, Hot Springs, Arkansas, United States

🇺🇸

Foamix Investigational Site # 222, Rogers, Arkansas, United States

and more 43 locations

A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.

Phase 2
Completed
Conditions
Acne Vulgaris
Interventions
Combination Product: FCD105
Other: Vehicle Foam
First Posted Date
2019-09-26
Last Posted Date
2021-02-05
Lead Sponsor
Vyne Therapeutics Inc.
Target Recruit Count
446
Registration Number
NCT04104685
Locations
🇺🇸

Foamix Institution #134, Bryant, Arkansas, United States

🇺🇸

Foamix Institution #121, Rogers, Arkansas, United States

🇺🇸

Foamix Institution #106, Encino, California, United States

and more 32 locations

Dermal Photo Allergic Skin Reaction

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2019-08-28
Last Posted Date
2019-08-28
Lead Sponsor
Vyne Therapeutics Inc.
Target Recruit Count
56
Registration Number
NCT04070755
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News

Vitiligo Treatment Pipeline Shows Promise with JAK Inhibitors and Novel Immunotherapies in Phase 3 Trials

Over 18 companies are actively developing 20+ pipeline therapies for vitiligo treatment, with JAK inhibitors leading the charge in late-stage clinical trials.

VYNE Therapeutics' Repibresib Gel Fails to Meet Primary Endpoints in Phase 2b Vitiligo Trial

VYNE Therapeutics announced that its phase 2b trial of repibresib gel in nonsegmental vitiligo failed to meet primary and key secondary endpoints, with only 19.5% of patients achieving F-VASI50 improvement compared to 23.4% on vehicle.

MindMed Appoints Matt Wiley as Chief Commercial Officer to Lead MM120 Launch Strategy

MindMed has appointed Matt Wiley as Chief Commercial Officer to oversee the commercial strategy for MM120 ODT, a potential treatment for generalized anxiety disorder and major depressive disorder.

VYNE Therapeutics Advances VYN201 and VYN202 in Vitiligo and Psoriasis Trials

VYNE Therapeutics completes enrollment for Phase 2b trial of VYN201 gel (repibresib) in nonsegmental vitiligo, with top-line data expected mid-2025.

VYN201 Shows Promise in Phase 1b Trial for Non-Segmental Vitiligo

A Phase 1b trial of VYN201 topical gel demonstrated safety and tolerability in patients with active non-segmental vitiligo (aNSV).

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