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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

A Randomized Study of the Efficacy of a New Intervention for Medication Adherence in Chronic Illness: Medications, Meaning and Me (The 3-M Study)

Not Applicable

Completed

Conditions: Self-management in Heart Failure

Interventions: Behavioral: CHIME 3-M
Behavioral: attention control

First Posted Date: 2014-10-07

Last Posted Date: 2016-08-22

Lead Sponsor: Duke University

Target Recruit Count: 87

Registration Number: NCT02258516

EXTEND Exercise Trial

Phase 2

Completed

Conditions: Non-metastatic, Hormone naïve Prostate Cancer

Interventions: Drug: Enzalutamide
Drug: Androgen deprivation therapy
Behavioral: Supervised exercise training

First Posted Date: 2014-10-03

Last Posted Date: 2019-04-18

Lead Sponsor: Duke University

Target Recruit Count: 26

Registration Number: NCT02256111

Locations: 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Acceptability and Feasibility of an ACT-Based Group to Improve Diabetes Self-Management

Phase 1

Withdrawn

Conditions: Type 1 Diabetes Mellitus

Interventions: Behavioral: Diabetes self-management group based on Acceptance and Commitment Therapy (ACT).

First Posted Date: 2014-10-03

Last Posted Date: 2015-06-12

Lead Sponsor: Duke University

Registration Number: NCT02256293

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

Not Applicable

Completed

Conditions: Traumatic Brain Injury
Chronic Pain
Posttraumatic Stress Disorders

Interventions: Device: NeuroSky MindWave Mobile

First Posted Date: 2014-09-11

Last Posted Date: 2020-01-18

Lead Sponsor: Duke University

Target Recruit Count: 41

Registration Number: NCT02237885

Locations: 🇺🇸
Duke University, Department of Psychiatry, Durham, North Carolina, United States

Natural History Study of Patients With Hypophosphatasia (HPP)

Recruiting

Conditions: Hypophosphatasia

First Posted Date: 2014-09-11

Last Posted Date: 2025-03-14

Lead Sponsor: Duke University

Target Recruit Count: 200

Registration Number: NCT02237625

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Function and Scoliosis Surgery

Completed

Conditions: Adolescent Idiopathic Scoliosis

First Posted Date: 2014-09-11

Last Posted Date: 2017-06-28

Lead Sponsor: Duke University

Target Recruit Count: 15

Registration Number: NCT02237248

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

SDOCT-GMPE Software

Not Applicable

Completed

Conditions: Glaucoma

Interventions: Device: SDOCT-GMPE software

First Posted Date: 2014-09-10

Last Posted Date: 2017-07-26

Lead Sponsor: Duke University

Target Recruit Count: 57

Registration Number: NCT02235454

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

The Effects of Potassium on Glucose Metabolism in African Americans

Phase 2

Completed

Conditions: Borderline Hypokalemia

Interventions: Drug: Placebo
Drug: K+ supplement

First Posted Date: 2014-09-10

Last Posted Date: 2017-05-23

Lead Sponsor: Duke University

Target Recruit Count: 61

Registration Number: NCT02236598

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Effects of Chemoradiation and Surgery on Cardiopulmonary Fitness and Tumor Neoplastic Phenotype in Gastrointestinal Malignancies

Not Applicable

Terminated

Conditions: Plan of Care Must Include Chemoradiation
Pathologically Proven Gastrointestinal Malignancy

Interventions: Other: Cardiopulmonary Exercise Test (CPET)

First Posted Date: 2014-09-10

Last Posted Date: 2017-07-11

Lead Sponsor: Duke University

Target Recruit Count: 8

Registration Number: NCT02235441

Locations: 🇺🇸
Joan Cahill, Durham, North Carolina, United States

Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure

Phase 2

Completed

Conditions: Heart Failure

Interventions: Drug: Spironolactone
Drug: Placebo

First Posted Date: 2014-09-09

Last Posted Date: 2017-06-14

Lead Sponsor: Duke University

Target Recruit Count: 360

Registration Number: NCT02235077

Locations: 🇺🇸
Southeastern Regional Medical Center, Lumberton, North Carolina, United States
🇺🇸
Metro Health System, Cleveland, Ohio, United States
🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States

and more 19 locations

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